Publication:
Axial psoriatic arthritis: The impact of underdiagnosed disease on outcomes in real life

dc.contributor.buuauthorDalkılıç, Ediz
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.scopusid6506739457tr_TR
dc.date.accessioned2023-01-11T06:29:47Z
dc.date.available2023-01-11T06:29:47Z
dc.date.issued2018-06-04
dc.descriptionÇalışmada 25 yazar bulunmaktadır. Bu yazarlardan sadece Bursa Uludağ Üniversitesi mensuplarının girişleri yapılmıştır.tr_TR
dc.description.abstractPsoriatic arthritis (PsA) may affect different joints, including the spine. The prevalence of spinal involvement is variable depending on the definition and a subset of patients have been identified in cohorts that do not have clinical features of axial disease and yet have imaging findings. Still, there is not a consensus on how and when to screen axial disease. In this study, we aimed to investigate factors associated with being underdiagnosed for axial psoriatic arthritis (axPsA) and its impacts on outcomes. Disease features and outcomes of axPsA according to the physician (n=415) were compared with patients with imaging findings only (sacroiliitis fulfilling the modified New York criteria, n=112), using data from a real-life PsA registry. Patients with imaging findings only were more frequently women (83/220 (37.7%) vs 29/122 (23.8%); p=0.008). This group also had higher peripheral disease activity (imaging only vs clinical AxPsA: mean (SD) tender joint count 5.3 (6.1) vs 3.3 (4.7), swollen joint count 1.9 (2.9) vs 1.2 (2.4); p<0.001 for both comparisons) and was less often treated using TNF inhibitors (16.1 vs 38.2%; p<0.001) than patients who were classified as axPsA. Patient-reported outcomes were similar in both groups. PsA patients, especially women with more severe peripheral disease, have a higher risk of being underdiagnosed for axPsA. The severity of peripheral symptoms may be a risk factor to mask the spinal features of PsA.en_US
dc.description.sponsorshipAbbvie, Novartisen_US
dc.description.sponsorshipSanofien_US
dc.description.sponsorshipUCBen_US
dc.description.sponsorshipPfizer Canadaen_US
dc.identifier.citationAydın, S. Z. vd. (2018). ''Axial psoriatic arthritis: the impact of underdiagnosed disease on outcomes in real life''. Clinical Rheumatology, 37(12), 3443-3448.en_US
dc.identifier.endpage3448tr_TR
dc.identifier.issn0770-3198
dc.identifier.issn1434-9949
dc.identifier.issue12tr_TR
dc.identifier.pubmed29948352tr_TR
dc.identifier.scopus2-s2.0-85048510844tr_TR
dc.identifier.startpage3443tr_TR
dc.identifier.urihttps://doi.org/10.1007/s10067-018-4173-4
dc.identifier.urihttps://link.springer.com/article/10.1007/s10067-018-4173-4
dc.identifier.urihttp://hdl.handle.net/11452/30379
dc.identifier.volume37tr_TR
dc.identifier.wos000451729300038
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.collaborationYurt dışıtr_TR
dc.relation.collaborationYurt içitr_TR
dc.relation.collaborationSanayitr_TR
dc.relation.journalClinical Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRheumatologyen_US
dc.subjectAxial diseaseen_US
dc.subjectPsoriatic arthritisen_US
dc.subjectRadiographyen_US
dc.subjectSpondyloarthropathyen_US
dc.subjectRecommendationsen_US
dc.subjectCriteriaen_US
dc.subject.emtreeTumor necrosis factor inhibitoren_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeAssociationen_US
dc.subject.emtreeAxial psoriatic arthritisen_US
dc.subject.emtreeCervical spineen_US
dc.subject.emtreeClinical featureen_US
dc.subject.emtreeClinical outcomeen_US
dc.subject.emtreeCohort analysisen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeDiagnostic erroren_US
dc.subject.emtreeDisease activityen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeJoint radiographyen_US
dc.subject.emtreeLumbar spineen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeModified new york criteriaen_US
dc.subject.emtreeMusculoskeletal disease assessmenten_US
dc.subject.emtreeMusculoskeletal system parametersen_US
dc.subject.emtreePatient-reported outcomeen_US
dc.subject.emtreePhysicianen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreePsoriatic arthritisen_US
dc.subject.emtreeReliabilityen_US
dc.subject.emtreeSacroiliac jointen_US
dc.subject.emtreeSacroiliitisen_US
dc.subject.emtreeSex differenceen_US
dc.subject.emtreeSpine radiographyen_US
dc.subject.emtreeSwollen joint counten_US
dc.subject.emtreeTender joint counten_US
dc.subject.emtreeUnderdiagnosisen_US
dc.subject.emtreeArthrographyen_US
dc.subject.emtreeComplicationen_US
dc.subject.emtreeDiagnostic imagingen_US
dc.subject.emtreeEpidemiologyen_US
dc.subject.emtreeInflammationen_US
dc.subject.emtreeMiddle ageden_US
dc.subject.emtreePrevalenceen_US
dc.subject.emtreePsoriatic arthritisen_US
dc.subject.emtreeRadiographyen_US
dc.subject.emtreeRegisteren_US
dc.subject.emtreeReproducibilityen_US
dc.subject.emtreeRheumatologyen_US
dc.subject.emtreeRisk factoren_US
dc.subject.emtreeSeverity of illness indexen_US
dc.subject.emtreeSpineen_US
dc.subject.emtreeStandardsen_US
dc.subject.emtreeTreatment outcomeen_US
dc.subject.emtreeTurkey (bird)en_US
dc.subject.meshAdulten_US
dc.subject.meshArthritis, psoriaticen_US
dc.subject.meshArthrographyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInflammationen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshPatient reported outcome measuresen_US
dc.subject.meshPrevalenceen_US
dc.subject.meshRadiographyen_US
dc.subject.meshRegistriesen_US
dc.subject.meshReproducibility of resultsen_US
dc.subject.meshRheumatologyen_US
dc.subject.meshRisk factorsen_US
dc.subject.meshSacroiliitisen_US
dc.subject.meshSeverity of illness indexen_US
dc.subject.meshSpineen_US
dc.subject.meshTreatment outcomeen_US
dc.subject.meshTurkeyen_US
dc.subject.scopusPustulosis Palmoplantaris; Secukinumab; Nail Diseasesen_US
dc.subject.wosRheumatologyen_US
dc.titleAxial psoriatic arthritis: The impact of underdiagnosed disease on outcomes in real lifeen_US
dc.typeArticle
dc.wos.quartileQ3en_US
dspace.entity.typePublication

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