Publication:
Synthesis of novel alkyl-sulfanyl 1,3,4-oxadiazolyl-1,3,5,7-tetraazatricyclic ammonium chloride type cationic surfactants

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Date

2015-03-01

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Wiley

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Abstract

A series of novel cationic surfactants bearing 1,3,4-oxadiazole and tetraazatricyclic ring structures were synthesized by alkyl chain elongation of 5-{10-[4-(hydroxymethyl)phenoxy]decyl}-2,3-dihydro-1,3,4-oxadiazole-2-thione with homologous series of alkyl bromides, followed by chlorination of the corresponding benzyl alcohols with thionyl chloride and quaternization of the obtained intermediates with hexamethylenetetramine.

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Gene delivery, In-vitro, Corrosion-inhibitors, Gemini surfactants, Carbon-steel, Lipids, Vivo, Alkylation, Cyclization, 1, 3, 4-oxadiazole, Lipids, Alkylation, Cyclization, 1, 3, 4-oxadiazole, Lipids, Science & technology, Physical sciences, Chemistry, organic, Chemistry

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