Publication:
Hematopoietic stem cell transplantation activities and HRQOL of refugee or asylum seeker children in Turkiye: A multicenter study

dc.contributor.authorGökcebay, Dilek Gürlek
dc.contributor.authorKüpeli, Serhan
dc.contributor.authorGürsel, Orhan
dc.contributor.authorBilir, Özlem Arman
dc.contributor.authorAkyay, Arzu
dc.contributor.authorPekpak, Esra
dc.contributor.authorAkbayram, Sinan
dc.contributor.authorÖncül, Yurday
dc.contributor.authorGüneş, Adalet Meral
dc.contributor.authorKırkız, Serap
dc.contributor.authorKılıç, Suar Çakı
dc.contributor.authorBozkaya, İkbal Ok
dc.contributor.authorÖzbek, Namık Yaşar
dc.contributor.buuauthorMERAL GÜNEŞ, ADALET
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentÇocuk Kemik İliği Nakli Ünitesi
dc.contributor.researcheridEXD-8400-2022
dc.date.accessioned2024-11-14T10:47:17Z
dc.date.available2024-11-14T10:47:17Z
dc.date.issued2022-10-07
dc.description.abstractBackground Refugee or asylum seekers (RAS) children are at increased risk of physical, developmental, and behavioral health issues. The aim of this study was to evaluate clinical and psychosocial outcomes of hematopoietic stem cell transplantation (HSCT) in RAS children and compare health-related quality of life (HRQOL) to those of Turkish peers. Methods This retrospective study included patients who underwent HSCT aged 0-18 years and completed 100-day post-transplant. The PedsQL 4.0 Generic Core Scale was used in children over 5 years old to compare HRQOL. Results A total of 166 RAS patients (M/F: 106 /60) underwent 174 HSCTs (six patients had two, and one had three HSCT) compared to 66 Turkish patients. The mean age of the patients in the RAS group was 7.8 +/- 4.9 years and similar to controls. A total of 124 patients (75%) were from Syria, and 49 (25%) were from other countries in the Middle East and Africa. The cause of migration was war in 121 (74%) RAS patients. Complications of HSCT were no different between the groups. However, the rate of neutropenic sepsis was significantly higher in the RAS group (p = 0.004). The total scores of HRQOL were not different between RAS and controls. In the RAS group, ratings of social functioning were lower in patients with consanguinity or non-malignant disease or who had match-related donors. Discussion Identifying areas of difficulty in subscales of HRQOL may help physicians to classify patients who need additional supportive care. Regular monitoring and supporting physical needs may result in better functional outcomes after HSCT.
dc.identifier.doi10.1111/petr.14397
dc.identifier.eissn1399-3046
dc.identifier.issn1397-3142
dc.identifier.issue8
dc.identifier.scopus2-s2.0-85139459414
dc.identifier.urihttps://doi.org/10.1111/petr.14397
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1111/petr.14397
dc.identifier.urihttps://hdl.handle.net/11452/47877
dc.identifier.volume26
dc.identifier.wos000864933900001
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherWiley
dc.relation.journalPediatric Transplantation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectQuality-of-life
dc.subjectPediatric-patients
dc.subjectMarrow
dc.subjectReliability
dc.subjectPedsql(tm)
dc.subjectRecipients
dc.subjectImpact
dc.subjectGraft
dc.subjectHematopoietic stem cell transplantation
dc.subjectQuality of life
dc.subjectRefugee children
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectPediatrics
dc.subjectTransplantation
dc.titleHematopoietic stem cell transplantation activities and HRQOL of refugee or asylum seeker children in Turkiye: A multicenter study
dc.typeArticle
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Çocuk Kemik İliği Nakli Ünitesi
local.indexed.atWOS
local.indexed.atScopus
relation.isAuthorOfPublication500825a8-5e0f-481f-a84f-d7fb8759c049
relation.isAuthorOfPublication.latestForDiscovery500825a8-5e0f-481f-a84f-d7fb8759c049

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