Publication:
Sleep measurements in women with dysthymic disorder and insomnia

dc.contributor.authorKotan, Zeynep
dc.contributor.authorBican, Aylin
dc.contributor.authorKotan, Vahap Ozan
dc.contributor.authorBora, İbrahim
dc.contributor.authorYalvac, Hayriye Dilek
dc.contributor.authorÖzkaya, Güven
dc.contributor.authorAkkaya, Cengiz
dc.contributor.buuauthorBİCAN DEMİR, AYLİN
dc.contributor.buuauthorBORA, İBRAHİM HAKKI
dc.contributor.buuauthorÖZKAYA, GÜVEN
dc.contributor.buuauthorAKKAYA, CENGİZ
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentBiyoistatistik Ana Bilim Dalı
dc.contributor.orcid0000-0003-0798-4850
dc.contributor.orcid0000-0002-1456-2499
dc.contributor.researcheridA-4421-2016
dc.contributor.researcheridENI-7759-2022
dc.contributor.researcheridCEN-7664-2022
dc.contributor.researcheridEKJ-8427-2022
dc.date.accessioned2024-07-30T11:35:51Z
dc.date.available2024-07-30T11:35:51Z
dc.date.issued2015-01-01
dc.description.abstractTo determine the effects of trazodone, mirtazapine and hydroxyzine on sleep profiles of dysthymic disorder (DD) women with selective serotonin reuptake inhibitor (SSRI) treatment and compare their polysomnographic measurements with controls. Among 36 patients trazodone receiving (n=9), mirtazapine receiving (n=8), hydroxyzine receiving (n=8) and only SSRI receiving (n=11) patients were compared to each other and to controls in terms of polysomnographic (PSG) findings. Rapid eye movements (REM) ratio and sleep onset time (SO) were higher; slow wave sleep (non-REM3) ratio and total sleep duration (TSD)) and sleep efficiency (SE) were lower in patients when compared with controls. Increased REM ratio and SO; decreased non-REM3 ratio and TSD and SE were found in both only SSRI receiving patients and hydroxyzine receiving patients when compared with controls. Only SSRI receiving patients also showed increased non-REM1 ratio. Trazodone or mirtazapine receiving patients showed no difference than controls. When PSG assessment is considered, it can be suggested that both trazodone and mirtazapine improve sleep problems in DD patients with SSRI treatment, but hydroxyzine does not.
dc.identifier.doi10.1111/sbr.12092
dc.identifier.endpage105
dc.identifier.issn1446-9235
dc.identifier.issue1
dc.identifier.startpage99
dc.identifier.urihttps://doi.org/10.1111/sbr.12092
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/full/10.1111/sbr.12092
dc.identifier.urihttps://hdl.handle.net/11452/43546
dc.identifier.volume13
dc.identifier.wos000347460300012
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherSpringer
dc.relation.journalSleep and Biological Rhythms
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectMajor depression
dc.subjectPsychiatric-disorders
dc.subjectEeg sleep
dc.subjectGeneralized anxiety
dc.subjectGender-differences
dc.subjectMirtazapine
dc.subjectTrazodone
dc.subjectMetaanalysis
dc.subjectProfiles
dc.subjectDysthymic disorder
dc.subjectHydroxyzine
dc.subjectInsomnia
dc.subjectMirtazapine
dc.subjectTrazodone
dc.subjectNeurosciences & neurology
dc.titleSleep measurements in women with dysthymic disorder and insomnia
dc.typeArticle
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Nöroloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Biyoistatistik Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Psikiyatri Ana Bilim Dalı
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relation.isAuthorOfPublication7674bbf4-9c63-42a4-b1e0-09ecdcb8f05a
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relation.isAuthorOfPublication.latestForDiscovery8b72317c-2cda-4511-bba9-51f797dadec4

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