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Determination of phenolic compounds in Prunella L. by liquid chromatography-diode array detection

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dc.contributor.buuauthorŞahin, Saliha
dc.contributor.buuauthorDemir, Cevdet
dc.contributor.buuauthorMalyer, Hulusi M.
dc.contributor.departmentFen Edebiyat Fakültesi
dc.contributor.departmentKimya Ana Bilim Dalı
dc.contributor.orcid0000-0003-1508-0181
dc.contributor.orcid0000-0002-9381-0410
dc.contributor.researcheridAAH-2892-2021
dc.contributor.researcheridABA-2005-2020
dc.contributor.scopusid15027401600
dc.contributor.scopusid7003565902
dc.contributor.scopusid6602736554
dc.date.accessioned2021-12-13T12:19:45Z
dc.date.available2021-12-13T12:19:45Z
dc.date.issued2011-07-15
dc.description.abstractFour species of Prunella L. (Prunella vulgaris L., Prunella laciniata L., Prunella grand:flora L. and Prunella orientalis Bornm.) belong to the family of Lamiaceae and representing popular Western and Chinese herbal medicine were examined for the content of phenolic compounds. Phenolic acids (rosmarinic acid, caffeic acid, ferulic acid, chlorogenic acid, protocatechuic acid), flavonoids (rutin, quercetin) in different quantitative proportions depending on extracts were determined by the rapid, selective and accurate method combining solvent/acid hydrolysis extraction and high performance liquid chromatographydiode array detection (HPLC-DAD). Water, methanol, butanol, acetonitrile, ethyl acetate, hexane and their acidic solutions were used to examine the efficiency of different solvent systems for the extraction of phenolic compounds. Acid hydrolysis extraction was established as the most suitable extraction method for phenolic compounds.
dc.identifier.citationŞahin, S. vd. (2011). "Determination of phenolic compounds in Prunella L. by liquid chromatography-diode array detection". Journal of Pharmaceutical and Biomedical Analysis, 55(5), 1227-1230.
dc.identifier.endpage1230
dc.identifier.issn0731-7085
dc.identifier.issn1873-264X
dc.identifier.issue5
dc.identifier.pubmed21498022
dc.identifier.scopus2-s2.0-79956123222
dc.identifier.startpage1227
dc.identifier.urihttps://doi.org/10.1016/j.jpba.2011.03.016
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0731708511001506
dc.identifier.urihttp://hdl.handle.net/11452/23212
dc.identifier.volume55
dc.identifier.wos000291129700050
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherElsevier
dc.relation.bap2009/38
dc.relation.journalJournal of Pharmaceutical and Biomedical Analysis
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectChemistry
dc.subjectPharmacology & pharmacy
dc.subjectPrunella L.
dc.subjectPhenolic compounds
dc.subjectHPLC-DAD
dc.subjectSolvent extraction
dc.subjectHydrolysis
dc.subjectPlant extract
dc.subjectFlavonoids
dc.subjectHPLC
dc.subject.emtreeAcetic acid ethyl ester
dc.subject.emtreeAcetonitrile
dc.subject.emtreeButanol
dc.subject.emtreeCaffeic acid
dc.subject.emtreeChlorogenic acid
dc.subject.emtreeFerulic acid
dc.subject.emtreeHexane
dc.subject.emtreeMethanol
dc.subject.emtreeProtocatechuic acid
dc.subject.emtreePhenol derivative
dc.subject.emtreePrunella vulgaris extract
dc.subject.emtreeQuercetin
dc.subject.emtreeRosmarinic acid
dc.subject.emtreeRutoside
dc.subject.emtreeSolvent
dc.subject.emtreeWater
dc.subject.emtreeAccuracy
dc.subject.emtreeArticle
dc.subject.emtreeDiode
dc.subject.emtreeDrug determination
dc.subject.emtreeExamination
dc.subject.emtreeHerbal medicine
dc.subject.emtreeHigh performance liquid chromatograph
dc.subject.emtreeHydrolysis
dc.subject.emtreeLiquid chromatography
dc.subject.emtreeNonhuman
dc.subject.emtreePriority journal
dc.subject.emtreePrunella
dc.subject.emtreePrunella grandiflora
dc.subject.emtreePrunella laciniata
dc.subject.emtreePrunella orientali
dc.subject.emtreeQuantitative analysis
dc.subject.emtreeSolution and solubility
dc.subject.meshChemistry techniques, analytical
dc.subject.meshChemistry, pharmaceutical
dc.subject.meshChromatography, high pressure liquid
dc.subject.meshChromatography, liquid
dc.subject.meshHydrolysis
dc.subject.meshPhenol
dc.subject.meshPlant extracts
dc.subject.meshPrunella
dc.subject.meshSolvents
dc.subject.meshWater
dc.subject.scopusPrunella; Machaeranthera; Derris
dc.subject.wosChemistry, analytical
dc.subject.wosPharmacology & pharmacy
dc.titleDetermination of phenolic compounds in Prunella L. by liquid chromatography-diode array detection
dc.typeArticle
dc.wos.quartileQ2
dspace.entity.typePublication
local.contributor.departmentFen Edebiyat Fakültesi/Kimya Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

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