Publication: Testicular adrenal rest tumors in patients with congenital adrenal hyperplasia
dc.contributor.buuauthor | Çakır, Esra Deniz Papatya | |
dc.contributor.buuauthor | Mutlu, Fatma Şentürk | |
dc.contributor.buuauthor | Eren, Erdal | |
dc.contributor.buuauthor | Paşa, Aliye Özlem | |
dc.contributor.buuauthor | Sağlam, Halil | |
dc.contributor.buuauthor | Tarım, Ömer | |
dc.contributor.department | Tıp Fakültesi | |
dc.contributor.department | Tıp Fakültesi | |
dc.contributor.department | Radyoloji Ana Bilim Dalı | |
dc.contributor.department | Çocuk Endokrinoloji Ana Bilim Dalı | |
dc.contributor.orcid | 0000-0003-0710-5422 | |
dc.contributor.orcid | 0000-0002-1684-1053 | |
dc.contributor.researcherid | C-7392-2019 | |
dc.contributor.researcherid | AAM-1734-2020 | |
dc.contributor.researcherid | AAH-1155-2021 | |
dc.contributor.scopusid | 37003613900 | |
dc.contributor.scopusid | 48061357900 | |
dc.contributor.scopusid | 36113153400 | |
dc.contributor.scopusid | 55270612300 | |
dc.contributor.scopusid | 35612700100 | |
dc.contributor.scopusid | 6701427186 | |
dc.date.accessioned | 2021-11-24T09:45:22Z | |
dc.date.available | 2021-11-24T09:45:22Z | |
dc.date.issued | 2012 | |
dc.description.abstract | Objective: Early diagnosis and treatment of testicular adrenal rest tumors (TART) is important for gonadal functions and fertility protection in boys with congenital adrenal hyperplasia (CAH). In this descriptive study, we investigated the prevalence of TART in boys with 21-hydroxylase deficient (21OHD) CAH followed in our pediatric endocrine clinic. Methods: The study group consisted of 14 male patients with a mean age of 9.6+/-5.1 (range: 0.8-18.3) years. Six (42.9%) of the 14 patients were diagnosed as having salt-wasting type (SW) and eight (57.1%) patients - as having the simple virilizing (SV) form of 21OHD. Mean age at diagnosis was 2.9+/-2.7 (range: 0.03-6.3) years. Two different radiologists performed scrotal ultrasonography. Chronological age, bone age, and anthropometric measurements were evaluated. Serum adrenocorticotropic hormone (ACTH), 17-alpha-hydroxyprogesterone (17OHP) and androstenedione levels were also evaluated in all patients during the follow-up period. Results: Scrotal ultrasonography revealed bilateral TART in two patients (14.3%) and testicular microlithiasis (TM) in four patients (28.6%). One patient had both TART and TM bilaterally. During the follow-up period, the mean serum adrenocorticotropic hormone, 17OHP and androstenedione levels in the total group of patients were 130.0+/-179.1 pg/mL (21.7-726.5), 5.8+/-3.3 ng/mL (0.8-11.4) and 4.3+/-4.1 (0.2-11.0) ng/mL, respectively. Conclusions: Microlithiasis or TART may be frequently encountered during the follow-up of patients with CAH. In order to prevent late complications including infertility, we suggest that ultrasonographic evaluations be performed yearly in all male CAH patients. | |
dc.identifier.citation | Çakır, E. D. P. vd. (2012). "Testicular adrenal rest tumors in patients with congenital adrenal hyperplasia". Journal of Clinical Research in Pediatric Endocrinology, 4(2), 94-100. | |
dc.identifier.endpage | 100 | |
dc.identifier.issn | 1308-5727 | |
dc.identifier.issn | 1308-5735 | |
dc.identifier.issue | 2 | |
dc.identifier.pubmed | 22672867 | |
dc.identifier.scopus | 2-s2.0-84863113855 | |
dc.identifier.startpage | 94 | |
dc.identifier.uri | https://doi.org/10.4274/jcrpe.563 | |
dc.identifier.uri | https://pubmed.ncbi.nlm.nih.gov/22672867/ | |
dc.identifier.uri | http://hdl.handle.net/11452/22785 | |
dc.identifier.volume | 4 | |
dc.identifier.wos | 000209012600008 | |
dc.indexed.wos | SCIE | |
dc.indexed.wos | BKCIS | |
dc.language.iso | en | |
dc.publisher | Galenos Yayıncılık | |
dc.relation.journal | Journal of Clinical Research in Pediatric Endocrinology | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Endocrinology & metabolism | |
dc.subject | Pediatrics | |
dc.subject | Testicular adrenal rest tumors | |
dc.subject | Testicular microlithiasis | |
dc.subject | Congenital adrenal hyperplasia | |
dc.subject.emtree | Androstenedione | |
dc.subject.emtree | Corticotropin | |
dc.subject.emtree | Cyproterone acetate | |
dc.subject.emtree | Fludrocortisone | |
dc.subject.emtree | Glucocorticoid | |
dc.subject.emtree | Growth hormone | |
dc.subject.emtree | Hydrocortisone | |
dc.subject.emtree | Hydroxyprogesterone | |
dc.subject.emtree | Leuprorelin | |
dc.subject.emtree | Tamoxifen | |
dc.subject.emtree | Adolescent | |
dc.subject.emtree | Adrenal cortex tumor | |
dc.subject.emtree | Adult | |
dc.subject.emtree | Age | |
dc.subject.emtree | Androstenedione blood level | |
dc.subject.emtree | Anthropometry | |
dc.subject.emtree | Article | |
dc.subject.emtree | Bone age | |
dc.subject.emtree | Cancer patient | |
dc.subject.emtree | Child | |
dc.subject.emtree | Clinical article | |
dc.subject.emtree | Clinical evaluation | |
dc.subject.emtree | Congenital adrenal hyperplasia | |
dc.subject.emtree | Controlled study | |
dc.subject.emtree | Descriptive research | |
dc.subject.emtree | Echography | |
dc.subject.emtree | Follow up | |
dc.subject.emtree | Gynecomastia | |
dc.subject.emtree | Hormone blood level | |
dc.subject.emtree | Human | |
dc.subject.emtree | Infant | |
dc.subject.emtree | Infertility | |
dc.subject.emtree | Male | |
dc.subject.emtree | Preschool child | |
dc.subject.emtree | Prevalence | |
dc.subject.emtree | Radiologist | |
dc.subject.emtree | Salt wasting | |
dc.subject.emtree | School child | |
dc.subject.emtree | Steroid 21 monooxygenase deficiency | |
dc.subject.emtree | Testis tumor | |
dc.subject.emtree | Tumor diagnosis | |
dc.subject.emtree | Virilization | |
dc.subject.mesh | 17-alpha-hydroxyprogesterone | |
dc.subject.mesh | Adolescent | |
dc.subject.mesh | Adrenal hyperplasia, congenital | |
dc.subject.mesh | Adrenal rest tumor | |
dc.subject.mesh | Adrenocorticotropic hormone | |
dc.subject.mesh | Age determination by skeleton | |
dc.subject.mesh | Androstenedione | |
dc.subject.mesh | Child | |
dc.subject.mesh | Child, preschool | |
dc.subject.mesh | Follow-up studies | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Male | |
dc.subject.mesh | Scrotum | |
dc.subject.mesh | Steroid 21-hydroxylase | |
dc.subject.mesh | Testicular neoplasms | |
dc.subject.mesh | Treatment outcome | |
dc.subject.mesh | Ultrasonography | |
dc.subject.scopus | Adrenal Cortex Tumor; Congenital Adrenal Hyperplasia; Testicular Neoplasms | |
dc.subject.wos | Endocrinology & metabolism | |
dc.subject.wos | Pediatrics | |
dc.title | Testicular adrenal rest tumors in patients with congenital adrenal hyperplasia | |
dc.type | Article | |
dc.type | Book Chapter | |
dspace.entity.type | Publication | |
local.contributor.department | Tıp Fakültesi/Çocuk Endokrinoloji Ana Bilim Dalı | |
local.contributor.department | Tıp Fakültesi/Radyoloji Ana Bilim Dalı | |
local.indexed.at | Scopus | |
local.indexed.at | WOS |
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