Yayın: HER-2/neu (c-erbB-2) oncoprotein in hyperplastic endometrial polyps detected in two cats
Tarih
Kurum Yazarları
Mısırlıoğlu, Deniz
Nak, Deniz
Özyiğit, Musa Özgür
Nak, Yavuz
Akkoç, Ahmet
Yazarlar
Danışman
Dil
Türü
Yayıncı:
Sage Publications
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Özet
The presence of HER-2/neu (c-erbB-2) oncoprotein, oestrogen-alpha. receptor (ER), and progesterone receptor (PR) in hyperplastic endometrial polyps (EPs) of two cats with cystic endometrial hyerplasia-pyometra (CEH-P) complex was investigated. Immunohistochemistry assay for ER, PR and c-erbB-2 oncoprotein in the glandular and stromal tissue of the Ell's was performed. ER and c-erbB-2 immunoreactivity,vas observed in the glandular epithelium of the EPs whereas PR immunoreactivity was detected only in the stromal fibroblasts. The c-erbB-2 oncoprotein may play a role with the ER in the pathogenesis of the hyperplastic EPs, although the role of this oncoprotein in the pathogenesis of EPs has yet to be determined.
Açıklama
Kaynak:
Anahtar Kelimeler:
Konusu
Epidermal-growth-factor, Progesterone-receptor expression, Estrogen, Pyometra, Features, Uterus, Alpha, Dog, Veterinary sciences
Alıntı
Mısırlıoğlu, D. vd. (2009). "HER-2/neu (c-erbB-2) oncoprotein in hyperplastic endometrial polyps detected in two cats". Journal of Feline Medicine and Surgery, 11(10), 885-888.