Yayın: Mn(OAC) 3 Induced C-4 arylations of quinazoline 3-oxides with arylboronic acids
Tarih
Kurum Yazarları
Yazarlar
Samandram, Rashinikumar
Korukçu, Meliha Çetin
Coşkun, Necdet
Danışman
Dil
Türü
Yayıncı:
Georg Thieme Verlag Kg
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Özet
The use of manganese triacetate as an oxidant component in the C-4 arylations of 2-aryl-quinazoline 3-oxides with arylboronic acids- is reported. The new protocol was applied to prepare new 2,4-di-arylated quinazoline 3-oxides in good to high yields. The method was shown to tolerate various substituents on both aromatic rings, and no complications such as deoxygenation or rearrangement to quinazolin-4(3H)-one was observed.
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Konusu
C-h activation, N-oxides, Quinoline, Functionalization, Amination, Access, Quinazoline, Quinazoline 3-oxide, C-h activation, Arylation, Arylboronic acids, Science & technology, Physical sciences, Chemistry, organic, Chemistry