Publication:
A Retrospective evaluation of the incidence and risk factors of nosocomial diarrhea in critically ill adult patients

dc.contributor.buuauthorÖzgür, Mustafa
dc.contributor.buuauthorGirgin, Nermin Kelebek
dc.contributor.buuauthorAkalın, Halis
dc.contributor.buuauthorİşçimen, Remzi
dc.contributor.buuauthorSınırtaş, Melda
dc.contributor.buuauthorKahveci, Ferda
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentAnesteziyoloji ve Reanimasyon Ana Bilim Dalı
dc.contributor.departmentMikrobiyoloji ve Enfeksiyon Hastalıkları Ana Bilim Dalı
dc.contributor.orcid0000-0001-8111-5958
dc.contributor.orcid0000-0003-4820-2288
dc.contributor.researcheridAAI-8104-2021
dc.contributor.researcheridAAG-9356-2021
dc.contributor.researcheridAAH-7250-2019
dc.contributor.researcheridHKP-2533-2023
dc.contributor.researcheridAAU-8952-2020
dc.contributor.scopusid55846946000
dc.contributor.scopusid55663009300
dc.contributor.scopusid57207553671
dc.contributor.scopusid16645821200
dc.contributor.scopusid6505818048
dc.contributor.scopusid6602405968
dc.date.accessioned2023-09-13T05:55:02Z
dc.date.available2023-09-13T05:55:02Z
dc.date.issued2016-01-02
dc.description.abstractIntroduction: Diarrhea is a commonly encountered complication in critically ill patients. It causes fluid and electrolyte loss, increases the workload of nurses, and prolongs the duration of hospitalization. The aim of this retrospective study was to investigate the incidence and risk factors associated with nosocomial diarrhea in adult patients treated in intensive care unit (ICU). Materials and methods: Records of 786 adult patients treated in the ICU between January 2004 and May 2009 were inspected retrospectively. Loose or watery stools occurring three times a day and more was considered as diarrhea. The control group included those patients who were treated in ICU at the same time as the patients with diarrhea, with similar demographic and clinic features. Results: It was established that of 786 patients, 78 (9.92%) developed diarrhea. The time lapse between admission to the ICU and the onset of diarrhea was 12.41 +/- 21.7 days, and the duration of diarrhea was 438 +/- 2.13 days. Compared to the control's (n=80), the rate of enteral feeding was higher in patients with diarrhea, enteral nutrition products of high concentration, proton pump inhibitors, medications containing sorbitol and Mg+2, clindamycin, and cephalosporins were used significantly more often (p=0.002, p=0.006, p=0.048, p=0.006, p=0.033, p=0.048). Furthermore, the length of stay in ICU was longer in these patients (p=0.043). Clostridium difficile toxin was determined to be positive in 11 patients with diarrhea (14.1%). These cases were older and had a longer ICU stay and duration of diarrhea (p=0.031, p=0.027, p=0.004). Conclusion: It was found that the patients with diarrhea had a high enteral nutrition infusion rate, and products concentration, a high level of drug usage such as proton pump inhibitors, antibiotics, and sorbitol, and a low albumin level. Nosoconzial diarrhea could also prolong the length of ICU stay in critically ill patients.
dc.identifier.citationÖzgür, M. vd. (2016). "A Retrospective evaluation of the incidence and risk factors of nosocomial diarrhea in critically ill adult patients". Acta Medica Mediterranea, 32(3), 741-746.
dc.identifier.endpage746
dc.identifier.issn0393-6384
dc.identifier.issn2283-9720
dc.identifier.issue3
dc.identifier.scopus2-s2.0-84994337303
dc.identifier.startpage741
dc.identifier.urihttps://doi.org/10.19193/0393-6384_2016_3_83
dc.identifier.urihttp://hdl.handle.net/11452/33831
dc.identifier.volume32
dc.identifier.wos000376693400012
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherCarbone Editore
dc.relation.journalActa Medica Mediterranea
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectGeneral & internal medicine
dc.subjectNosocomial diarrhea
dc.subjectIntensive care
dc.subjectCritically ill
dc.subjectEnteral feeding
dc.subjectClostridium difficile infection
dc.subjectClostridium-difficile infection
dc.subjectIntensive-care-unit
dc.subjectGastrointestinal complications
dc.subjectAntibiotics
dc.subjectMulticenter
dc.subjectSymptoms
dc.subject.emtreeAminoglycoside antibiotic agent
dc.subject.emtreeAntibiotic agent
dc.subject.emtreeCarbapenem
dc.subject.emtreeCephalosporin derivative
dc.subject.emtreeClindamycin
dc.subject.emtreeEnema
dc.subject.emtreeHistamine H2 receptor antagonist
dc.subject.emtreeLaxative
dc.subject.emtreeMacrolide
dc.subject.emtreeMagnesium
dc.subject.emtreePenicillin derivative
dc.subject.emtreeProton pump inhibitor
dc.subject.emtreeQuinoline derived antiinfective agent
dc.subject.emtreeQuinolone
dc.subject.emtreeSorbitol
dc.subject.emtreeVancomycin
dc.subject.emtreeAdult
dc.subject.emtreeClostridium difficile infection
dc.subject.emtreeControlled study
dc.subject.emtreeCritically ill patient
dc.subject.emtreeDemography
dc.subject.emtreeDisease duration
dc.subject.emtreeEnteric feeding
dc.subject.emtreeFemale
dc.subject.emtreeHospital
dc.subject.emtreeHospital admission
dc.subject.emtreeHospital infection
dc.subject.emtreeHuman
dc.subject.emtreeIncidence
dc.subject.emtreeInfection risk
dc.subject.emtreeIntensive care unit
dc.subject.emtreeLength of stay
dc.subject.emtreeLoose feces
dc.subject.emtreeMajor clinical study
dc.subject.emtreeMale
dc.subject.emtreeRetrospective study
dc.subject.emtreeArticle
dc.subject.scopusEnteric Feeding; Diarrhea; Critical Illness
dc.subject.wosMedicine, general & internal
dc.titleA Retrospective evaluation of the incidence and risk factors of nosocomial diarrhea in critically ill adult patients
dc.typeArticle
dc.wos.quartileQ4
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Anesteziyoloji ve Reanimasyon Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Mikrobiyoloji ve Enfeksiyon Hastalıkları Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

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