Solution blown of pla nanofiber containing ozonated mormodica oil and its microcapsules to obtain antibacterial medical textiles surfaces

Abstract

In the scope of the study, it was aimed to obtain antibacterial nanofiber surfaces containing Momordica oil, its ozonated oil form and its microcapsules forms. First of all, Mormodica oil was exposed to ozone gas for 135 min. After that, crude and ozonated mormodica oil were microencapsulated by using simple coacervation. Subsequently, %10 PLA polymer solution were prepared and used for obtaining PLA nanofiber surface by using solution blowing spinning. Besides, PLA polymer solution were mixed with crude mormodica oil, ozonated mormodica oil and their microcapsules forms and then these solutions were spun by using solution blowing spinning. Obtained ozonated oil, microcapsules and nanofiber surfaces were characterized via measurement of total unsaturated fatty acid amount in the oils, scanning electron microscope, FT-IR analysis and antibacterial activity test. The data showed that mormodica oil were ozonated. Microencapsulation process was done successfully and obtained nanofiber containing mormodica oil and its microcapsules. Moreover antibacterial activity showed that mormodica oil and ozonated mormodica oil showed antibacterial activity against to S.aureus and E.coli bacteria according to the disc diffusion method. The nanofiber surfaces containing ozonated oil and its microcapsules showed antibacterial activity against to S.aureus and E.coli bacteria according to the ASTM E 2149-01 method. As a result, it was obtained biodegradable nanofiber containing microcapsules and showing antibacterial activity.