Publication:
Effect of vitamin E supplementation on post-exercise plasma lipid peroxidation and blood antioxidant status in smokers: with special reference to haemoconcentration effect

dc.contributor.buuauthorGür, Esma Sürmen
dc.contributor.buuauthorÖztürk, Ercan
dc.contributor.buuauthorGür, Hakan
dc.contributor.buuauthorPündük, Zekine
dc.contributor.buuauthorTuncel, Pınar
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentSpor Hekimliği Ana Bilim Dalı
dc.contributor.departmentBiyokimya Ana Bilim Dalı
dc.contributor.orcid0000-0001-7377-9682
dc.contributor.researcheridAAG-7327-2021
dc.contributor.researcheridI-9594-2017
dc.date.accessioned2021-06-29T11:01:34Z
dc.date.available2021-06-29T11:01:34Z
dc.date.issued1999
dc.description.abstractThe oxidative effects were investigated of exhausting exercise in smokers, and the possible protective role of 400 mg.day(-1) vitamin E (Vit E) supplementation over a period of 28 days. The subjects exercised to exhaustion including concentric-eccentric contractions following maximal cycling. The haematocrit and haemoglobin, leucocyte (WBC), plasma lactic acid (La) and malondialdehyde (MDA), erythrocyte superoxide dismutase (SOD) and glutathione peroxidase (GPx), serum Vit E and ceruloplasmin (CER) concentrations were measured pre and post exercise. Supplementation increased Vit E concentrations 28% and 31% in the controls and the smokers, respectively. Cigarette smoking and/or Vit E supplementation did not influence plasma lipid peroxidation or the antioxidant status at rest. Exercise caused significant haemoconcentration in all groups. When the post-exercise concentrations were adjusted for haemoconcentration, a significant elevation in La concentrations due to exercise was observed in all groups. Similarly, there were significant elevations in the adjusted WBC counts in all groups except the Vit E supplemented controls. The MDA concentrations on the other hand, when adjusted for haemoconcentration, did not exhibit any difference due to exercise. Exercise did not affect the GPx and CER activities either, while causing a SOD activity loss in all groups except the Vit E supplemented non-smokers. Serum Vit E concentrations diminished significantly in all groups after exercise. Postexercise plasma MDA and blood antioxidant concentrations were not altered by smoking. The results would suggest that plasma volume changes should always be taken into account when assessing post-exercise plasma concentrations and that smoking and exercise do not have an additional collective effect on plasma lipid peroxidation and the dose of Vit E administered was insufficient to maintain the serum concentrations after exercise.
dc.identifier.citationGür, E. S. vd. (1999). "Effect of vitamin E supplementation on post-exercise plasma lipid peroxidation and blood antioxidant status in smokers: with special reference to haemoconcentration effect". European Journal of Applied Physiology, 79(6), 472-478.
dc.identifier.endpage478
dc.identifier.issn1439-6319
dc.identifier.issue6
dc.identifier.pubmed10344454
dc.identifier.scopus2-s2.0-0345299199
dc.identifier.startpage472
dc.identifier.urihttps://doi.org/10.1007/s004210050539
dc.identifier.urihttps://link.springer.com/article/10.1007/s004210050539
dc.identifier.urihttp://hdl.handle.net/11452/20904
dc.identifier.volume79
dc.identifier.wos000080106100002
dc.indexed.scopusScopus
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherSpringer
dc.relation.journalEuropean Journal of Applied Physiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPhysiology
dc.subjectSport sciences
dc.subjectFree radical
dc.subjectExhausting exercise
dc.subjectVitamin E
dc.subjectSmoking
dc.subjectAntioxidant
dc.subjectTocopherol mobilization
dc.subjectSubmaximal exercise
dc.subjectCigarette smokers
dc.subjectOxidative damage
dc.subjectFree-radicals
dc.subjectSerum
dc.subjectEnzymes
dc.subjectAscorbate
dc.subject.wosPhysiology
dc.subject.wosSport sciences
dc.titleEffect of vitamin E supplementation on post-exercise plasma lipid peroxidation and blood antioxidant status in smokers: with special reference to haemoconcentration effect
dc.typeArticle
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Biyokimya Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Spor Hekimliği Ana Bilim Dalı
local.indexed.atWOS
local.indexed.atScopus

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