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Thymic tumors and outcomes after radiotherapy

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OBJECTIVESWe evaluated the results of treatment in patients with thymic tumors treated with postoperative adjuvant radiotherapy.METHODSEighteen patients were treated median 5400 cGy radiotherapy between 1995-2010. Diagnosis of patients were thymoma (n=10), thymic carcinoma (n=7), thymic neuroendocrin carcinoma (n=1). RO resection was made on 12 of them. According to prognostic stratification with Masaoka stage and WHO classification, there were 5 good, 7 moderate, and 6 poor risk patients. Survival was calculated from diagnosis.RESULTSA total of 33% patients were recurred median 29.5 months with 34 months follow-up. Local control, median overall and disease-free survival for all patients were 77%, 113 months, and 105 months. Local control for good, moderate, poor risk groups were found 100%, 71%, 50%. There were significant differences survival rates for Masaoka stage, RO resection, and prognostic groups.CONCLUSIONPrognostic risk classification was found to be better predictive in terms of local control and survival.

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Thymic tumor, Adjuvant radiotherapy, Local control, Prognostic group, Survival, Science & technology, Life sciences & biomedicine, Oncology

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