Publication:
Prevalence of obesity in paediatric psoriasis and its impact on disease severity and progression

dc.contributor.authorErgün, Tülin
dc.contributor.authorGençosmanoğlu, Dilek Seçkin
dc.contributor.authorKarakoç, Aydıner Elif
dc.contributor.authorSalman, Andaç
dc.contributor.authorTekin, Burak
dc.contributor.authorAlpsoy, Erkan
dc.contributor.authorCakıroğlu, Aylın
dc.contributor.authorOnsun, Nahide
dc.contributor.buuauthorBülbül, Emel Baskan
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentDermatoloji Ana Bilim Dalı
dc.contributor.scopusid6602518817
dc.date.accessioned2022-11-03T06:42:34Z
dc.date.available2022-11-03T06:42:34Z
dc.date.issued2017
dc.description.abstractBackground/Objectives: The current literature suggests there is a possible connection between paediatric psoriasis and obesity. However, there is a paucity of research on the influence of increased adiposity on the severity of paediatric psoriasis and disease progression. We aimed to compare the prevalence of being overweight or obese in paediatric psoriasis patients and controls and assess the potential impact of being overweight/obese on disease severity and progression of disease. Methods: This multicentre prospective case-control study included 289 psoriasis patients (aged < 18 years) treated and followed up by one of the four university hospitals in Turkey. The control group consisted of 151 consecutive age-matched and sex-matched children who lacked a personal or family history of psoriasis. The participants' characteristics, psoriasis-related parametres (e.g., initial subtype, psoriasis area and severity index, presence of psoriatic arthritis) and body mass index were determined. Results: The difference between the prevalence of being overweight/obese among psoriatics (28%) and the control group (19%) was significant (P = 0.024). Being overweight/obese had no significant impact on disease severity and unresponsiveness to topical treatment. Within a median follow-up time of 12 months, 23% of our patients with localised disease at disease onset progressed to generalised disease. The impact of being overweight/obese on disease progression was found to be non-significant; however, disease duration was found to have a significant impact on disease progression (P = 0.026). Conclusions: Although it is not associated with disease severity and course, increased bodyweight may be a health problem for psoriatic children.
dc.description.sponsorshipSchering Plough Corporation
dc.description.sponsorshipAbbVie
dc.description.sponsorshipMerck & Company
dc.description.sponsorshipJohnson & Johnson Johnson & Johnson USA Janssen Biotech Inc
dc.description.sponsorshipMerck & Company
dc.identifier.citationErgün, T. vd. (2017). ''Prevalence of obesity in paediatric psoriasis and its impact on disease severity and progression''. Australasian Journal of Dermatology, 58(4), E182-E182.
dc.identifier.endpageE187
dc.identifier.issn0004-8380
dc.identifier.issn1440-0960
dc.identifier.issue4
dc.identifier.pubmed27242061
dc.identifier.scopus2-s2.0-84971569506
dc.identifier.startpageE182
dc.identifier.urihttps://doi.org/10.1111/ajd.12491
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1111/ajd.12491
dc.identifier.urihttp://hdl.handle.net/11452/29333
dc.identifier.volume58
dc.identifier.wos000419099100004
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherWiley
dc.relation.collaborationYurt içi
dc.relation.journalAustralasian Journal of Dermatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDermatology
dc.subjectDisease progression
dc.subjectDisease severity
dc.subjectObesity
dc.subjectPaediatric psoriasis
dc.subjectMetabolic syndrome
dc.subjectGuttate psoriasis
dc.subjectChildren
dc.subjectAssociation
dc.subjectComorbidities
dc.subjectEpidemiology
dc.subjectMetaanalysis
dc.subjectAdolescents
dc.subjectMmanagement
dc.subjectOverweight
dc.subject.emtreeBetamethasone
dc.subject.emtreeCalcipotriol
dc.subject.emtreeCorticosteroid
dc.subject.emtreeVitamin D derivative
dc.subject.emtreeArticle
dc.subject.emtreeBody mass
dc.subject.emtreeCase control study
dc.subject.emtreeChild
dc.subject.emtreeControlled study
dc.subject.emtreeDisease classification
dc.subject.emtreeDisease course
dc.subject.emtreeDisease duration
dc.subject.emtreeDisease severity
dc.subject.emtreeEmotional stress
dc.subject.emtreeFemale
dc.subject.emtreeFollow up
dc.subject.emtreeHuman
dc.subject.emtreeKolmogorov smirnov test
dc.subject.emtreeMajor clinical study
dc.subject.emtreeMale
dc.subject.emtreeMulticenter study
dc.subject.emtreeObesity
dc.subject.emtreePreschool child
dc.subject.emtreePsoriasis
dc.subject.emtreePsoriasis area and severity index
dc.subject.emtreeSchool child
dc.subject.emtreeAdolescent
dc.subject.emtreeChildhood obesity
dc.subject.emtreeClinical trial
dc.subject.emtreeComplication
dc.subject.emtreeDisease exacerbation
dc.subject.emtreeObesity
dc.subject.emtreePrevalence
dc.subject.emtreeProspective study
dc.subject.emtreePsoriasis
dc.subject.emtreeSeverity of illness index
dc.subject.emtreeTurkey (bird)
dc.subject.meshAdolescent
dc.subject.meshBody mass index
dc.subject.meshCase-control studies
dc.subject.meshChild
dc.subject.meshDisease progression
dc.subject.meshFemale
dc.subject.meshMale
dc.subject.meshOverweight
dc.subject.meshPediatric obesity
dc.subject.meshPrevalence
dc.subject.meshProspective Studies
dc.subject.meshPsoriasis
dc.subject.meshSeverity of Illness Index
dc.subject.meshTurkey
dc.subject.meshHumans
dc.subject.scopusPustulosis Palmoplantaris; Psoriatic Arthritis; Metabolic Syndrome
dc.subject.wosDermatology
dc.titlePrevalence of obesity in paediatric psoriasis and its impact on disease severity and progression
dc.typeArticle
dc.wos.quartileQ3
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Dermatoloji Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

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