Selective digestive decontamination can be an infection-prevention regimen for the intoxicated patients

Abstract

Selective Digestive Decontamination (SDD) the risk factors for the respiratory tract of the intoxicated patients receiving have never been investigated. Thity intoxicated patients who were admitted to the intensive care unit are included in this study. The three different methods of SDD were randomly studied. SDD, SDD with systemic Antibiotic Therapy (AT) and only systemic AT were applied to groups of ten patients each. On adinission, samples were taken from the oropharynx and trachea before the first administration of SDD and then every three days. In cultures, Gram-negative bacilli (Pseudomonas aeruginosa, Klebsiella pneumoniae) and Gram-positive cocci (Staphylococcus aureus) colonizations were significantly higher in Group SDD+AT and Group AT than Group SDD (p<0.005, p<0.05). The pulmonary infection and pulmonary consolidation on chest X-rays were significantly more visible in Group SDD+AT and Group AT (p<0.05). As a conclusion, SDD is ail effective method to prevent intoxicated patients from respiratory system infection. Moreover, SDD can be an infection-preverition regimen in a biological event. © 2009 Academic Journals Inc.