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Sustainable synthetic approaches using [C(16)Im][Oxa] as a flexible organocatalyst and DFT studies toward 3,4-dihydropyrimidinones and benzoxazines

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Yıldırım, Ayhan

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Kaya, Yunus

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Springer

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Abstract

Easily accessible 1-hexadecyl-1H-imidazol-3-ium oxalate is highly efficient Bronsted type acidic catalyst for the selected multicomponent one-pot reactions. The short reaction times, easy workup procedures, and green metal-free conditions for the reactions make the protocols more advantageous. Further reactions proceeded smoothly in good to excellent yields with high purity. To investigate mechanism of the multicomponent reactions, DFT calculations were performed.

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Chemistry, Mannich reaction, Biginelli reaction, Organocatalysis, Green chemistry, Quantum chemical calculations, One-pot synthesis, Multicomponent biginelli reaction, Acidic ionic liquid, Solvent-free, Efficient synthesis, Pyrimidinone derivatives, Aromatic-aldehydes, Green synthesis, Catalyst, Dihydropyrimidinones

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Yıldırım, A. ve Kaya, Y. (2017). ''Sustainable synthetic approaches using [C(16)Im][Oxa] as a flexible organocatalyst and DFT studies toward 3,4-dihydropyrimidinones and benzoxazines''. Monatshefte für Chemie, 148(6), 1085-1094.

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