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Comparison of the effects of buparvaquone and paromomycin on oocyst excretion and clinical parameters in diarrheal calves naturally infected with cryptosporidiosis

dc.contributor.authorEvci, Fatma Zehra
dc.contributor.authorŞentürk, Sezgin
dc.contributor.buuauthorEvci, Fatma Zehra
dc.contributor.buuauthorŞENTÜRK, SEZGİN
dc.contributor.departmentBursa Uludağ Üniversitesi/Veteriner Fakültesi/İç Hastalıkları Anabilim Dalı
dc.contributor.orcid0000-0002-2767-7690
dc.contributor.orcid0000-0002-2465-9913
dc.contributor.researcheridHOR-5415-2023
dc.contributor.researcheridJRN-6743-2023
dc.date.accessioned2024-09-13T05:57:21Z
dc.date.available2024-09-13T05:57:21Z
dc.date.issued2022-10-01
dc.description.abstractCryptosporidium spp. is an obligate intracellular parasite that infects a wide variety of hosts. Young calves are particularly susceptible to infection. In the present study, we investigated the effects of buparvaquone and paromomycin on oocyte shedding and clinical parameters in calves naturally infected with cryptosporidiosis. Twenty calves with naturally occurring cryptosporidiosis were divided into two groups (n=10, each). A single dose of 2.5 mg/ kg buparvaquone was administered intramuscularly to one group, while the animals in the other group received 100 mg/kg/day paromomycin orally for seven days. On day 7, oocyst shedding (p<0.001) was reduced, and sucking reflex (p=0.002) and mental status (p=0.034) were improved in calves treated with buparvaquone. Our results suggest that applying a single dose of buparvaquone injection can be an excellent alternative to complex treatment methods applied to calves with cryptosporidiosis in the field regarding the economics and practicability.
dc.identifier.doi10.12681/jhvms.27509
dc.identifier.endpage4784
dc.identifier.issn1792-2720
dc.identifier.issue4
dc.identifier.startpage4779
dc.identifier.urihttps://doi.org/10.12681/jhvms.27509
dc.identifier.urihttps://ejournals.epublishing.ekt.gr/index.php/jhvms/article/view/27509
dc.identifier.urihttps://hdl.handle.net/11452/44686
dc.identifier.volume73
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherHellenic Veterinary Medical Soc
dc.relation.journalJournal of The Hellenic Veterinary Medical Society
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTherapeutic-efficacy
dc.subjectOutbreak
dc.subjectChemoprophylaxis
dc.subjectHalofuginone
dc.subjectPatterns
dc.subjectGiardia
dc.subjectCryptosporidiosis
dc.subjectCalves
dc.subjectBuparvaquone
dc.subjectDiarrhea
dc.subjectParomomycin
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectVeterinary sciences
dc.titleComparison of the effects of buparvaquone and paromomycin on oocyst excretion and clinical parameters in diarrheal calves naturally infected with cryptosporidiosis
dc.typeArticle
dspace.entity.typePublication
relation.isAuthorOfPublication6289c31c-57ea-4497-a128-74a5f15e7e87
relation.isAuthorOfPublication.latestForDiscovery6289c31c-57ea-4497-a128-74a5f15e7e87

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