Publication:
Importance of MRI in showing the early period erosive alterations during wrist involvement in rheumatoid arthritis

dc.contributor.buuauthorGökalp, Gökhan
dc.contributor.buuauthorYazıcı, Zeynep
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentRadyoloji Ana Bilim Dalı
dc.contributor.researcheridAAI-2303-2021
dc.contributor.researcheridAAI-2336-2021
dc.contributor.scopusid8312505100
dc.contributor.scopusid6701668723
dc.date.accessioned2022-11-04T11:32:22Z
dc.date.available2022-11-04T11:32:22Z
dc.date.issued2010-02-16
dc.description.abstractObjectives: In this study, we aimed to evaluate the efficacy of magnetic resonance imaging (MRI) in demonstrating erosive alterations during the early period of rheumatoid arthritis (RA). Patients and methods: Twenty-one wrists of 14 patients (11 females, 3 males; mean age 54 years; range 37 to 64 years) diagnosed with RA by clinical data and laboratory results were examined with MRI. The disease activity was determined by C-reactive protein and erythrocyte sedimentation rates. Wrist radiographies of all the patients were either normal or had suspicious signs. The presence of bone erosion was evaluated in 15 different regions (8 carpal bones, 5 metacarpal heads, 1 distal radius, and 1 distal ulna). Coronal and axial T1-weighted spin echo (SE) images with and without fat suppression, coronal T2-weighted turbo SE images with fat suppression, and coronal T1-weighted SE images with fat suppression following administration of intravenous gadopenteate dimeglumine were obtained. Results: In all cases, the wrist radiographs were either normal or exhibited suspicious findings. Bone erosion was found in 73 (81.1%) different sites in carpal bones, four different sites in distal radius (4.4%), four (4.4%) different sites in distal ulna, and nine (10%) different sites in proximal metacarpal heads. While capitatum (27.3%) and triquetrum (24.6%) were the most commonly affected sites, pisiforme (1.6) was found be the least affected site. Among the 21 wrist MRIs showing erosion, nine (42.8%) had synovitis, three (14.2%) had tenosynovitis, two (9.5%) had bursitis, and seven (33.3%) had bone marrow edema. Conclusion: Magnetic resonance imaging may be an effective diagnostic method for the determination of early period joint involvement in RA cases.
dc.description.abstractAmaç: Bu çalışmada, romatoid artritin (RA) erken dönem eroziv değişikliklerinin ortaya konmasında, manyetik resonans görüntülemenin (MRG) etkinliği değerlendirildi. Hastalar ve yöntemler: Klinik veriler ve laboratuvar sonuçlarıyla RA tanısı konulan 14 hastada (11 kadın, 3 erkek; ort yaş 54 yıl; dağılım 37-64 yıl) 21 el bileği MRG ile incelendi. Hastalık aktivitesi C-reaktif protein ve eritrosit sedimantasyon oranı ile belirlendi. Hastaların hepsinde el bileği grafisi normaldi ya da şüpheli bulgular vardı. Kemik erozyonlarının varlığı 15 farklı bölgede (8 karpal kemik, 5 metakarp başı, 1 distal radius ve 1 distal ulna) değerlendirildi. Yağ baskılamalı ve yağ baskılamasız koronal ve aksiyal T1-ağırlıklı spin eko (SE) görüntüleri, yağ baskılamalı T2-ağırlıklı koronal turbo SE görüntüleri ve intravenöz gadopentetat dimeglumin verilmesinden sonra yağ baskılamalı T1-ağırlıklı koronal SE görüntüleri elde edildi. Bulgular: Olguların hepsinde el bileği grafisi ya normaldi ya da şüpheli bulgular vardı. Karpal kemiklerde 73 (%81.1) farklı bölgede, distal radiusta dört (%4.4) farklı bölgede, distal ulnada dört (%4.4) farklı bölgede, proximal metakarp başlarında dokuz (%10) farklı bölgede kemik erozyonu tespit edildi. Kapitatum (%27.3) ve triquetrum (%24.6) en çok ekilenen bölge iken, pisiforme en az etkilenen bölge (%1.6) olarak tespit edildi. Erozyon saptanan 21 elbileği MRG’sinin dokuzunda (%42.8) sinovit, üçünde tenosinovit (%14.2), ikisinde bursit (%9.5) ve yedisinde kemik iliği ödemi (%33.3) vardı. Sonuç: Manyetik resonans görüntüleme RA'lı olgularda erken dönem eklem tutulumunu saptamada etkin bir tanı yöntemi olabilir.
dc.identifier.citationGökalp, G. ve Yazıcı, Z. (2011). "Importance of MRI in showing the early period erosive alterations during wrist involvement in rheumatoid arthritis". Turkish Journal of Rheumatology, 26(2), 103-110.
dc.identifier.endpage110
dc.identifier.issn1309-0291
dc.identifier.issue2
dc.identifier.scopus2-s2.0-79959642041
dc.identifier.startpage103
dc.identifier.urihttps://doi.org/10.5606/tjr.2011.016
dc.identifier.urihttps://www.archivesofrheumatology.org/full-text/399
dc.identifier.urihttp://hdl.handle.net/11452/29384
dc.identifier.volume26
dc.identifier.wos000295972800003
dc.indexed.scopusScopus
dc.indexed.trdizinTrDizin
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherTurkish League Against Rheumatism
dc.relation.journalTurkish Journal of Rheumatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectRheumatology
dc.subjectErosion
dc.subjectMagnetic resonance imaging
dc.subjectRheumatoid arthritis
dc.subjectReference image atlas
dc.subjectConventional radiography
dc.subjectInflammatory arthritis
dc.subjectComputed-tomography
dc.subjectBone erosions
dc.subjectProgression
dc.subjectJoints
dc.subjectSynovitis
dc.subjectDisease
dc.subjectEdema
dc.subjectErozyon
dc.subjectManyetik rezonans görüntüleme
dc.subjectRomatoid artrit
dc.subject.emtreeC reactive protein
dc.subject.emtreeGadolinium pentetate meglumine
dc.subject.emtreeAdult
dc.subject.emtreeArticle
dc.subject.emtreeBone erosion
dc.subject.emtreeBone marrow edema
dc.subject.emtreeBursitis
dc.subject.emtreeCapitate bone
dc.subject.emtreeClinical article
dc.subject.emtreeClinical effectiveness
dc.subject.emtreeControlled study
dc.subject.emtreeDiagnostic value
dc.subject.emtreeDisease activity
dc.subject.emtreeElectron spin resonance
dc.subject.emtreeErythrocyte sedimentation rate
dc.subject.emtreeFemale
dc.subject.emtreeHuman
dc.subject.emtreeImage quality
dc.subject.emtreeMale
dc.subject.emtreeMetacarpal bone
dc.subject.emtreeNuclear magnetic resonance imaging
dc.subject.emtreePisiform bone
dc.subject.emtreeRadius
dc.subject.emtreeRheumatoid arthritis
dc.subject.emtreeTenosynovitis
dc.subject.emtreeUlna
dc.subject.emtreeWrist disease
dc.subject.emtreeWrist radiography
dc.subject.scopusUltrasound; Juvenile Arthritis; Rheumatology
dc.subject.wosRheumatology
dc.titleImportance of MRI in showing the early period erosive alterations during wrist involvement in rheumatoid arthritis
dc.title.alternativeRomatoid artritte el bileği tutulumu sırasında MRG’nin erken dönem erozif değişikliklerin ortaya konmasındaki önemi
dc.typeArticle
dc.wos.quartileN/A
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Radyoloji Ana Bilim Dalı
local.indexed.atTrDizin
local.indexed.atWOS
local.indexed.atScopus

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