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Hypothermia in neuronal protection

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Lippincott Williams & Wilkins

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During the past decade, it has been repeatedly shown that mild to moderate hypothermia (32-34 degreesC) reduces neurologic injury in animal models of focal or global ischemia, and of traumatic injury. This has led to renewed interest in the application of hypothermia for managing head injury, stroke, and cardiac arrest and for undertaking aneurysm surgery. This article reviews the relevant literature and presents the authors' experience with intracerebral hemorrhage treated under hypothermia.

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Aneurysm surgery, Hypothermia, Intracerebral hemorrhage, Neuronal protection, Cerebral-artery occlusion, Head-injured patients, Traumatic brain injury, Kinase-II, Ischemıc cell-damage, Protein, Mild hypothermia, Moderate hypothermia, Circulatory arrest, Forebrain ischemia, Postischemic hypothermia, Neurosciences & neurology, Surgery

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Alkan, T. vd. (2002). "Hypothermia in neuronal protection". Neurosurgery Quarterly, 11(2), 96-111.

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