Regional oxygen saturation and acute kidney injury in premature infants

Abstract

Background Decreased renal blood flow plays a vital role in the etiology of acute kidney injury (AKI). In this study, we aim to investigate the role of renal regional oxygen saturation (rSO(2)) reductions in predicting AKI in the first 24 h of life.Methods One hundred premature babies with a gestational age of <= 32 weeks were included. Renal and cerebral rSO(2)s were monitored for 24 h by near-infrared spectroscopy. Infants were followed up for the first 7 days for the diagnosis of AKI.Results Infants' median gestational age was 29 (23-32) weeks, and their birthweight was 1,192 +/- 355 g. It was found that the renal rSO(2) values were lower in the first 24 h of life in patients who developed AKI, and this decrease was statistically significant in the first 6 h of life.Conclusions The low renal rSO(2) values in the early hours of life in premature babies may have a role in predicting AKI.