Publication:
Acute colchicine intoxication during clarithromycin administration in patients with chronic renal failure

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Date

2006

Authors

Akdağ, İbrahim
Ersoy, Alpaslan
Kahvecioğlu, Serdar
Güllüoğlu, Mustafa
Dilek, Kamil

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Publisher

Springer Heidelberg

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Abstract

Colchicine is an effective antiinflammatory medication. It should be used with great caution, however, in patients requiring dialysis. Coadministration of colchicine and macrolides may impair colchicine elimination, resulting in excess drug exposure and toxicity. We report 2 renal failure cases of colchicine intoxication occurring with the administration of clarithromycin.

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Keywords

Urology & nephrology, Peritoneal dialysis, Gout, Familial mediterranean fever, Colchicine toxicity, Clarithromycin, Chronic renal failure, Overdose, Toxicity

Citation

Akdağ, İ. vd. (2006). ''Acute colchicine intoxication during clarithromycin administration in patients with chronic renal failure''. Journal of Nephrology, 19(4), 515-517.

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