Publication:
The role of low 25-Hydroxyvitamin D levels in preterm infants with late-onset sepsis

dc.contributor.buuauthorDoğan, Pelin
dc.contributor.buuauthorÖzkan, Hilal
dc.contributor.buuauthorKöksal, Nilgün
dc.contributor.buuauthorÇelebi, Solmaz
dc.contributor.buuauthorBağcı, Onur
dc.contributor.buuauthorTopçu, Merve
dc.contributor.buuauthorVaral Güney, İpek
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentÇocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.contributor.departmentÇocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.contributor.departmentÇocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.contributor.departmentEnfeksiyon Hastalıkları Ana Bilim Dalı
dc.contributor.departmentNeonatoloji Ana Bilim Dalı
dc.contributor.researcheridAAI-5981-2020
dc.contributor.scopusid55316686500
dc.contributor.scopusid16679325400
dc.contributor.scopusid7003323615
dc.contributor.scopusid7006095295
dc.contributor.scopusid20733563300
dc.contributor.scopusid57187985200
dc.contributor.scopusid57197818259
dc.date.accessioned2022-11-22T09:41:09Z
dc.date.available2022-11-22T09:41:09Z
dc.date.issued2020-01-23
dc.description.abstractIntroduction: We investigated the association between low 25-hydroxyvitamin D (25-OHD) levels and late-onset sepsis (LOS) in preterm infants (<37 weeks). Methods: Infants with culture-proven LOS were the study group, infants without LOS were the controls. 25-OHD levels were compared between these groups. Low vitamin D was defined as 25-OHD <= 15 ng/ml. Maternal 25-OHD levels were compared to their infant's level. Results: 108 infants were included. The study group was significantly younger (p = 0.02) with significantly lower 25-OHD levels (p < 0.001). Multivariable logistic regression analyses revealed that infants with low 25-OHD levels were 7.159 (95%CI: 1.402-36.553, p = 0.018) times more likely to develop LOS. A positive correlation was detected between maternal and neonatal 25-OHD levels for both study and control groups (r = 0.425, p = 0.009; r = 0.739, p < 0.001, respectively). Conclusions: Low 25-OHD levels are associated with an increased risk of developing LOS development in preterm infants
dc.identifier.citationDoğan, P. vd. (2020). "The role of low 25-Hydroxyvitamin D levels in preterm infants with late-onset sepsis". Fetal and Pediatric Pathology, 40(6), 571-580.
dc.identifier.endpage580
dc.identifier.issn1551-3815
dc.identifier.issue6
dc.identifier.pubmed32065014
dc.identifier.scopus2-s2.0-85079704563
dc.identifier.startpage571
dc.identifier.urihttps://doi.org/10.1080/15513815.2020.1725941
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.1080/15513815.2020.1725941
dc.identifier.urihttp://hdl.handle.net/11452/29533
dc.identifier.volume40
dc.identifier.wos000514508400001
dc.indexed.scopusScopus
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherTaylor & Francis
dc.relation.journalFetal and Pediatric Pathology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectLate-onset sepsis
dc.subjectPreterm
dc.subjectVitamin D
dc.subjectVitamin-D deficiency
dc.subjectNeonatal sepsis
dc.subjectRisk
dc.subjectSupplementation
dc.subjectPathology
dc.subjectPediatrics
dc.subject.emtree25 Hydroxyvitamin D
dc.subject.emtree25-Hydroxyvitamin D
dc.subject.emtreeVitamin D
dc.subject.emtreeArticle
dc.subject.emtreeControlled study
dc.subject.emtreeDisease association
dc.subject.emtreeDisease severity
dc.subject.emtreeFemale
dc.subject.emtreeHuman
dc.subject.emtreeInfant
dc.subject.emtreeMajor clinical study
dc.subject.emtreeMale
dc.subject.emtreePrematurity
dc.subject.emtreeProspective study
dc.subject.emtreeSepsis
dc.subject.emtreeVitamin blood level
dc.subject.emtreeVitamin D deficiency
dc.subject.emtreeNewborn
dc.subject.meshHumans
dc.subject.meshInfant
dc.subject.meshInfant, newborn
dc.subject.meshInfant, premature
dc.subject.meshSepsis
dc.subject.meshVitamin D
dc.subject.meshVitamin D deficiency
dc.subject.scopusErgocalciferols; Supplementation; Calcitriol Receptors
dc.subject.wosPathology
dc.subject.wosPediatrics
dc.titleThe role of low 25-Hydroxyvitamin D levels in preterm infants with late-onset sepsis
dc.typeArticle
dc.wos.quartileQ4
dc.wos.quartileQ4
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı/Neonatoloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı/Enfeksiyon Hastalıkları Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
local.indexed.atPubMed
local.indexed.atWOS
local.indexed.atScopus

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