The use of psychotropic drugs in renal diseases

Abstract

The use of psychotropic drugs in patients with renal impairment is one of the main challenges of clinicians, as some of the drugs are metabolized or excreted through the kidneys. General knowledge in this particular field of medicine is mostly derived from studies involving healthy subjects. There are only a few studies that include patients with renal impairment. The general principle in this group of patients is to begin with a lower dose and titrate to higher doses under monitorization. It is also recommended to avoid drugs that are known to be metabolized or excreted through the kidneys.