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Regio- and diastereoselective synthesis of (E)-3-(2-aminochromen-4-yl)-6-aryl-substituted fulvenes

Küçük Resim

Akademik Birimler

Kurum Yazarları

Coşkun, Necdet

Yazarlar

Koz, Gamze
Şahin, Onur

Danışman

Dil

Türü

Yayıncı:

Walter de Gruyter Gmbh

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Özet

A practical base-catalyzed route was developed for the regio- and diastereoselective synthesis of (E)-3-aminochromene-6-aryl-disubstituted fulvenes in high yields up to 94% starting with the Michael addition of cyclopentadiene to 2-iminochromenes in the key step.

Açıklama

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Konusu

Chemistry, Aminochromene, Base catalysis, Cyclopentadiene, Fulvene, Michael addition, Facile synthesis, Michael reaction, Derivatives, 2-amino-4h-chromenes, Cytotoxicity, Inhibitors, Thiourea, Agents, Addition reactions, Catalysis, Olefins, Aminochromene, Base catalysis, Cyclopentadienes, Fulvene, Michael additions, Stereoselectivity, Anticancer drugs

Alıntı

Koz, G. vd. (2016). "Regio- and diastereoselective synthesis of (E)-3-(2-aminochromen-4-yl)-6-aryl-substituted fulvenes". Zeitschrift fur Naturforschung-Section B Journal of Chemical Sciences, 71(9), 945-951.

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