Publication:
Epileptic seizures in cerebral venous sinus thrombosis: Subgroup analysis of VENOST study

dc.contributor.buuauthorBakar, Mustafa
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentNöroloji Ana Bilim Dalı
dc.contributor.researcheridEKN-8251-2022
dc.contributor.scopusid26643051200
dc.date.accessioned2022-12-26T05:46:20Z
dc.date.available2022-12-26T05:46:20Z
dc.date.issued2020-02-28
dc.descriptionÇalışmada 38 yazar bulunmaktadır. Bu yazarlardan sadece Bursa Uludağ Üniversitesi mensuplarının girişleri yapılmıştır.
dc.description.abstractPurpose: The aim of this study is to evaluate the presence and prognostic impact of early seizures in cerebral venous sinus thrombosis patients (CVST). Method: VENOST is a retrospective and prospective national multicenter observational study. CVST patients with or without epileptic seizures (ES) were analyzed and compared in terms of demographic and imaging data, causative factors, clinical variables, and prognosis in a total of 1126 patients. Results: The mean age of the patients in the ES group was 39.73 +/- 12.64 and 40.17 +/- 14.02 years in the non-ES group (p > 0.05). Epileptic seizures were more common (76.6 %) in females (p < 0.001). Early ES occurred in 269 of 1126 patients (23.9 %). Epileptic seizures mainly presented in the acute phase (71.4 %) of the disease (p < 0.001). Majority of these (60.5 %) were in the first 24 h of the CVST. The most common neurological signs were focal neurologic deficits (29.9 %) and altered consciousness (31.4 %) in the ES group. Superior sagittal sinus (SSS) and cortical veins (CV) involvement were the most common sites of thrombosis and the mostly related etiology were found puerperium in seizure group (30.3 % vs 13.9 %). Patients with seizures had worse outcome in the first month of the disease (p < 0.001) but these did not have any influence thereafter. Conclusions: In this largest CVST cohort (VENOST) reported female sex, presence of focal neurological deficits and altered consciousness, thrombosis of the SSS and CVs, hemorrhagic infarction were risk factors for ES occurrence in patients with CVST.
dc.identifier.citationUluduz, D. vd. (2020). "Epileptic seizures in cerebral venous sinus thrombosis: Subgroup analysis of VENOST study". Seizure, 78, 113-117.
dc.identifier.endpage117
dc.identifier.issn1059-1311
dc.identifier.issn1532-2688
dc.identifier.pubmed32353818
dc.identifier.scopus2-s2.0-85083703251
dc.identifier.startpage113
dc.identifier.urihttps://doi.org/10.1016/j.seizure.2020.02.017
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S1059131120300595
dc.identifier.urihttp://hdl.handle.net/11452/30072
dc.identifier.volume78
dc.identifier.wos000537574100019
dc.indexed.scopusScopus
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherW B Saunders
dc.relation.collaborationYurt içi
dc.relation.collaborationSanayi
dc.relation.journalSeizure
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCerebrovascular disease
dc.subjectEpilepsy
dc.subjectEarly seizure
dc.subjectCerebral venous sinus thrombosis
dc.subjectRisk-factors
dc.subjectVein
dc.subjectPuerperium
dc.subjectPregnancy
dc.subjectNeurosciences & neurology
dc.subject.emtreeAnticonvulsive agent
dc.subject.emtreeOral contraceptive agent
dc.subject.emtreeAdult
dc.subject.emtreeAge
dc.subject.emtreeArticle
dc.subject.emtreeBrain hemorrhage
dc.subject.emtreeBrain infarction
dc.subject.emtreeBrain radiography
dc.subject.emtreeBrain vein
dc.subject.emtreeCerebral sinus thrombosis
dc.subject.emtreeCerebral venous sinus thrombosis
dc.subject.emtreeClinical feature
dc.subject.emtreeCohort analysis
dc.subject.emtreeConsciousness disorder
dc.subject.emtreeControlled study
dc.subject.emtreeCortical vein
dc.subject.emtreeDemography
dc.subject.emtreeDisease duration
dc.subject.emtreeFamily history
dc.subject.emtreeFemale
dc.subject.emtreeFocal neurologic deficit
dc.subject.emtreeGender
dc.subject.emtreeHuman
dc.subject.emtreeInfection
dc.subject.emtreeMajor clinical study
dc.subject.emtreeMale
dc.subject.emtreeMalignant neoplasm
dc.subject.emtreeMedical parameters
dc.subject.emtreeMethodology
dc.subject.emtreeNeuroimaging
dc.subject.emtreeNeurologic disease
dc.subject.emtreeObservational study
dc.subject.emtreePregnancy
dc.subject.emtreePriority journal
dc.subject.emtreePrognosis
dc.subject.emtreeProspective study
dc.subject.emtreePuerperium
dc.subject.emtreeRetrospective study
dc.subject.emtreeRisk factor
dc.subject.emtreeSagittal sinus thrombosis
dc.subject.emtreeSeizure
dc.subject.emtreeSubgroup analysis
dc.subject.emtreeBrain hemorrhage
dc.subject.emtreeBrain infarction
dc.subject.emtreeCerebral sinus thrombosis
dc.subject.emtreeClinical trial
dc.subject.emtreeComplication
dc.subject.emtreeConsciousness disorder
dc.subject.emtreeEpilepsy
dc.subject.emtreeMiddle aged
dc.subject.emtreeMulticenter study
dc.subject.emtreeNuclear magnetic resonance imaging
dc.subject.emtreePathophysiology
dc.subject.emtreePrognosis
dc.subject.emtreeSeizure
dc.subject.meshAdult
dc.subject.meshCerebral hemorrhage
dc.subject.meshCerebral infarction
dc.subject.meshConsciousness disorders
dc.subject.meshEpilepsy
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMagnetic resonance imaging
dc.subject.meshMale
dc.subject.meshMiddle aged
dc.subject.meshPrognosis
dc.subject.meshProspective studies
dc.subject.meshRetrospective studies
dc.subject.meshSeizures
dc.subject.meshSinus thrombosis, intracranial
dc.subject.scopusCerebral Sinus Thrombosis; Vein Thrombosis; Superior Sagittal Sinus
dc.subject.wosClinical neurology
dc.subject.wosNeurosciences
dc.titleEpileptic seizures in cerebral venous sinus thrombosis: Subgroup analysis of VENOST study
dc.typeArticle
dc.wos.quartileQ3
dc.wos.quartileQ3
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Nöroloji Ana Bilim Dalı
local.indexed.atPubMed
local.indexed.atWOS
local.indexed.atScopus

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