Publication:
Evaluating the effect of the number of wire of flow diverter stents on the nonstagnated region formation in an aneurysm sac using lagrangian coherent structure and hyperbolic time analysis

dc.contributor.authorMutlu, Onur
dc.contributor.authorOlcay, Ali Bahadır
dc.contributor.buuauthorBilgin, Cem
dc.contributor.buuauthorHakyemez, Bahattin
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentRadyoloji Ana Bilim Dalı
dc.contributor.orcid0000-0002-3425-0740
dc.contributor.researcheridHHS-7433-2022
dc.contributor.researcheridAAI-2318-2021
dc.contributor.scopusid57200617643
dc.contributor.scopusid6602527239
dc.date.accessioned2024-02-09T11:00:18Z
dc.date.available2024-02-09T11:00:18Z
dc.date.issued2020-01
dc.description.abstractBackground: Giant aneurysms at carotid arteries are typically treated with flow diverter (FD) stents in the clinic. Although the goal of an FD stent is to direct most of the blood flow into the main artery, not much is known regarding the effects of wire number an FD possesses on the hemodynamics inside the aneurysm. Methods: In this study, 48-, 72-, and 96-wire FD stents were separately implanted into the site of aneurysm of a 45-year-old woman to evaluate the effects of the FD's number of wires on fluid flow behavior in the aneurysm sac. Time evolution of both finite-time Lyapunov exponent (FTLE) and hyperbolic time fields in the aneurysm sac were calculated by using computational fluid dynamics along with Lagrangian coherent structure (LCS) methods. Results: The computations reveal that a 48-wire FD stent allows a large amount of blood to enter inside the aneurysm sac revealing scattered nonstagnant flow zones formation. Besides, time-dependent results of LCS analysis show that most of the blood flow is diverted into the main artery when 72- and 96-wire number Surpass brand FD stents are separately implanted into the site of the aneurysm, yielding a small amount of blood flow to penetrate into the aneurysm sac. Conclusions: Furthermore, FTLE and hyperbolic time field plots are in good agreement with the patient's digital subtraction angiography image captured 3.5 minutes after 72-wire Surpass brand FD stent implantation.
dc.identifier.citationMutlu, O. vd. (2020) ."Evaluating the effect of the number of wire of flow diverter stents on the nonstagnated region formation in an aneurysm sac using lagrangian coherent structure and hyperbolic time analysis". World Neurosurgery, 133, e666-e682.
dc.identifier.doihttps://doi.org/10.1016/j.wneu.2019.09.116
dc.identifier.endpageE682
dc.identifier.issn1878-8750
dc.identifier.issn1878-8769
dc.identifier.pubmed31568908
dc.identifier.scopus2-s2.0-85074725931
dc.identifier.startpageE666
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S1878875019325574
dc.identifier.urihttps://hdl.handle.net/11452/39609
dc.identifier.volume133
dc.identifier.wos000503993700131
dc.indexed.scopusScopus
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherElsevier Science
dc.relation.collaborationYurt içi
dc.relation.journalWorld Neurosurgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.relation.tubitak117M491
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectNeurosciences & neurology
dc.subjectSurgery
dc.subjectComputational fluid dynamics
dc.subjectLagrangian coherent structure
dc.subjectStagnated and nonstagnated fluid flow zones
dc.subjectWire number of a flow diverter stent
dc.subjectBlood-flow
dc.subjectIntracranial aneurysms
dc.subjectEmbolization device
dc.subjectLeft-ventricle
dc.subjectStagnation
dc.subjectDiversion
dc.subjectTransport
dc.subjectVelocity
dc.subjectArteries
dc.subjectVolume
dc.subject.emtreeAdult
dc.subject.emtreeArticle
dc.subject.emtreeBlood flow
dc.subject.emtreeCarotid artery aneurysm
dc.subject.emtreeCase report
dc.subject.emtreeCirculation time
dc.subject.emtreeClinical article
dc.subject.emtreeComputational fluid dynamics
dc.subject.emtreeDigital subtraction angiography
dc.subject.emtreeEndovascular aneurysm repair
dc.subject.emtreeFemale
dc.subject.emtreeHuman
dc.subject.emtreeHyperbolic time analysis
dc.subject.emtreeImplantation
dc.subject.emtreeLagrangian coherent structure
dc.subject.emtreeMiddle aged
dc.subject.emtreeBiological model
dc.subject.emtreeComputer simulation
dc.subject.emtreeDevices
dc.subject.emtreeEndovascular surgery
dc.subject.emtreeHemodynamics
dc.subject.emtreeHydrodynamics
dc.subject.emtreeIntracranial aneurysm
dc.subject.emtreePhysiology
dc.subject.emtreeStent
dc.subject.meshAngiography, digital subtraction
dc.subject.meshComputer simulation
dc.subject.meshEndovascular procedures
dc.subject.meshFemale
dc.subject.meshHemodynamics
dc.subject.meshHumans
dc.subject.meshHydrodynamics
dc.subject.meshIntracranial aneurysm
dc.subject.meshMiddle aged
dc.subject.meshModels, biological
dc.subject.meshStents
dc.subject.scopusArtificial Embolization; Diverters; Stents
dc.subject.wosClinical neurology
dc.subject.wosSurgery
dc.titleEvaluating the effect of the number of wire of flow diverter stents on the nonstagnated region formation in an aneurysm sac using lagrangian coherent structure and hyperbolic time analysis
dc.typeArticle
dc.wos.quartile
dc.wos.quartileN/A
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Radyoloji Ana Bilim Dalı
local.indexed.atPubMed
local.indexed.atWOS
local.indexed.atScopus

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