Publication:
Histological evaluation of wound healing performance of electrospun poly(vinyl alcohol)/sodium alginate as wound dressing in vivo

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dc.contributor.buuauthorCoşkun, Gökçe
dc.contributor.buuauthorKaraca, Esra
dc.contributor.buuauthorÖzyurtlu, Mustafa
dc.contributor.buuauthorÖzbek, Serhat
dc.contributor.buuauthorYermezler, Aysun
dc.contributor.buuauthorÇavuşoğlu, İlkin
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentMühendislik Fakültesi
dc.contributor.departmentTekstil Mühendisliği Bölümü
dc.contributor.departmentPlastik ve Rekonstrüktif Cerrahi Ana Bilim Dalı
dc.contributor.departmentHistoloji ve Embriyoloji Ana Bilim Dalı
dc.contributor.orcid0000-0003-1777-3977
dc.contributor.orcid0000-0002-9156-2214
dc.contributor.researcheridAAS-8480-2020
dc.contributor.researcheridAFT-8971-2022
dc.contributor.researcheridAAH-5441-2021
dc.contributor.scopusid56094840400
dc.contributor.scopusid17344029200
dc.contributor.scopusid39962152600
dc.contributor.scopusid7005245657
dc.contributor.scopusid55938747300
dc.contributor.scopusid6602910240
dc.date.accessioned2022-09-12T08:49:01Z
dc.date.available2022-09-12T08:49:01Z
dc.date.issued2014
dc.description.abstractPoly(vinyl alcohol)/sodium alginate nanofibrous mats were produced by electrospinning method at optimum process parameters. Evaluation of alginate-based electrospun nanofibrous mats as a wound dressing material and their comparison to commercially available wound dressings produced with conventional methods were carried out in vivo. Tissue specimens were examined histopathologically on 4th, 6th, 15th, 21st postoperative days. In contrast to other dressings it was observed that nanofibrous mat could survive on the wound crust in early stages of healing. In terms of epithelization, epidermis characteristics, vascularization and formation of hair follicles, nanofibrous mat showed the best healing performance. This could be explained with presence of nanofibrous mat acting as an artificial skin on the wound region until new tissue regenerated.
dc.identifier.citationCoşkun, G. vd. (2014). "Histological evaluation of wound healing performance of electrospun poly(vinyl alcohol)/sodium alginate as wound dressing in vivo". Bio-Medical Materials and Engineering, 24(2), 1527-1536.
dc.identifier.endpage1536
dc.identifier.issn0959-2989
dc.identifier.issn1878-3619
dc.identifier.issue2
dc.identifier.pubmed24642979
dc.identifier.scopus2-s2.0-84897398165
dc.identifier.startpage1527
dc.identifier.urihttps://doi.org/10.3233/BME-130956
dc.identifier.urihttp://hdl.handle.net/11452/28642
dc.identifier.volume24
dc.identifier.wos000333059600010
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherIos Press
dc.relation.journalBio-Medical Materials and Engineering
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.relation.tubitak108M396
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectElectrospinning
dc.subjectNanofiber
dc.subjectAlginate
dc.subjectWound dressing
dc.subjectHistological evaluation
dc.subjectIn vivo
dc.subjectNormal human keratinocytes
dc.subjectNanofibrous membrane
dc.subjectSodium alginate
dc.subjectFibers
dc.subjectEngineering
dc.subjectMaterials science
dc.subjectArtificial organs
dc.subjectBiomaterials
dc.subjectPolyvinyl alcohols
dc.subjectTissue
dc.subjectConventional methods
dc.subjectElectrospinning method
dc.subjectHistological evaluation
dc.subjectIn-vivo
dc.subjectPost-operative days
dc.subjectProcess parameters
dc.subjectWound dressing materials
dc.subjectWound dressings
dc.subjectNanofibers
dc.subject.emtreeAlginic acid
dc.subject.emtreeCecalgum
dc.subject.emtreeChlorhexidine acetate
dc.subject.emtreeNanofiber
dc.subject.emtreePolyvinyl alcohol
dc.subject.emtreeUnclassified drug
dc.subject.emtreeAnimal experiment
dc.subject.emtreeArticle
dc.subject.emtreeConnective tissue
dc.subject.emtreeControlled study
dc.subject.emtreeElectrospinning
dc.subject.emtreeEpidermis
dc.subject.emtreeEpithelization
dc.subject.emtreeHair follicle
dc.subject.emtreeHistopathology
dc.subject.emtreeIn vivo study
dc.subject.emtreeMale
dc.subject.emtreeNonhuman
dc.subject.emtreePostoperative period
dc.subject.emtreePriority journal
dc.subject.emtreeVascularization
dc.subject.emtreeWound dressing
dc.subject.emtreeWound healing
dc.subject.meshAlginates
dc.subject.meshAnimals
dc.subject.meshBiocompatible materials
dc.subject.meshGlucuronic acid
dc.subject.meshHexuronic acids
dc.subject.meshMale
dc.subject.meshNanofibers
dc.subject.meshPolyvinyl alcohol
dc.subject.meshRabbits
dc.subject.meshWound healing
dc.subject.scopusChitosan; Electrospinning; Nanofibers
dc.subject.wosEngineering, biomedical
dc.subject.wosMaterials science, biomaterials
dc.titleHistological evaluation of wound healing performance of electrospun poly(vinyl alcohol)/sodium alginate as wound dressing in vivo
dc.typeArticle
dc.wos.quartileQ3 (Engineering, biomedical)
dc.wos.quartileQ4 (Materials science, biomaterials)
dspace.entity.typePublication
local.contributor.departmentMühendislik Fakültesi/Tekstil Mühendisliği Bölümü
local.contributor.departmentTıp Fakültesi/Plastik ve Rekonstrüktif Cerrahi Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Histoloji ve Embriyoloji Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

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