Publication: Immune reconstitution inflammatory syndrome. A case of postpartum tuberculosis
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KAZAK, ESRA
HEPER, YASEMİN
Akalın, Halis
Gürcüoğlu, Emel
Yılmaz, Emel
Hakyemez, Bahattin
Coşkun, Funda
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Aves
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Abstract
Immunorestitution disease or immune reconstitution inflammatory syndrome was initially described in HIV/AIDS patients under antiretroviral therapy. Although there were a decrease in viral load, control of viral replication and an increase in CD4+ T lymphocyte counts, the appearance of different forms of opportunistic infections and deterioration in their clinical status were observed in these patients. This clinical deterioration is a result of an excessive inflammatory response against previously diagnosed or asymptomatic opportunistic pathogens or undefined antigens. Recently, this syndrome was defined in HIV- negative patients and in other cases such as development of paradoxical response during antituberculosis therapy. In this report we present a case with postpartum tuberculosis from the perspective of immunorestitution disease
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Keywords
Immune reconstitution inflammatory syndrome, Tuberculosis, Science & technology, Life sciences & biomedicine, Medicine, general & internal, Microbiology, General & internal medicine, Microbiology