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Healthcare-associated Gram-negative bloodstream infections: Antibiotic resistance and predictors of mortality

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dc.contributor.buuauthorYılmaz, Emel
dc.contributor.buuauthorAkalın, Halis
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentEnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı
dc.contributor.orcid0000-0002-3894-1231
dc.contributor.researcheridAAU-8952-2020
dc.contributor.scopusid22037135100
dc.contributor.scopusid57207553671
dc.date.accessioned2022-10-27T11:02:40Z
dc.date.available2022-10-27T11:02:40Z
dc.date.issued2016-12
dc.descriptionÇalışmada 28 yazar bulunmaktadır. Bu yazarlardan sadece Bursa Uludağ Üniversitesi mensubu yazarların girişleri yapılmıştır.
dc.description.abstractThis article describes the prevalence of antibiotic resistance and predictors of mortality for healthcare-associated (HA) Gram-negative bloodstream infections (GN-BSI). In total, 831 cases of HA GN-BSI from 17 intensive care units in different centres in Turkey were included; the all-cause mortality rate was 44%. Carbapenem resistance in Klebsiella pneumoniae was 38%, and the colistin resistance rate was 6%. Multi-variate analysis showed that age > 70 years [odds ratio (OR) 2, 95% confidence interval (CI) 1.22-3.51], central venous catheter use (OR 2.1, 95% CI 1.09-4.07), ventilator- associated pneumonia (OR 1.9, 95% CI 1.1-3.16), carbapenem resistance (OR 1.8, 95% CI 1.11-2.95) and APACHE II score (OR 1.1, 95% CI 1.07-1.13) were significantly associated with mortality.
dc.identifier.citationErgönül, O. vd. (2016). "Healthcare-associated Gram-negative bloodstream infections: Antibiotic resistance and predictors of mortality". Journal of Hospital Infection, 94(4), 381-385.
dc.identifier.endpage385
dc.identifier.issn0195-6701
dc.identifier.issn1532-2939
dc.identifier.issue4
dc.identifier.pubmed27717604
dc.identifier.scopus2-s2.0-84996899090
dc.identifier.startpage381
dc.identifier.urihttps://doi.org/10.1016/j.jhin.2016.08.012
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0195670116303280
dc.identifier.urihttp://hdl.handle.net/11452/29241
dc.identifier.volume94
dc.identifier.wos000389233700014
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherW B Saunders
dc.relation.collaborationYurt içi
dc.relation.collaborationSanayi
dc.relation.journalJournal of Hospital Infection
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPublic, environmental & occupational health
dc.subjectlthInfectious diseases
dc.subjectBloodstream
dc.subjectGram-negative
dc.subjectHealthcare
dc.subjectKlebsiella-pneumoniae
dc.subjectOutcomes
dc.subjectImpactenterobacteriaceae
dc.subjectEpidemiology
dc.subjectSurveillance
dc.subjectBacteremia
dc.subjectProgram
dc.subject.emtreeAminoglycoside antibiotic agent
dc.subject.emtreeAntibiotic agent
dc.subject.emtreeCarbapenem
dc.subject.emtreeCephalosporin
dc.subject.emtreeColistin
dc.subject.emtreePiperacillin plus tazobactam
dc.subject.emtreeQuinoline derived antiinfective agent
dc.subject.emtreeAcinetobacter baumannii
dc.subject.emtreeAdult
dc.subject.emtreeAPACHE
dc.subject.emtreeArticle
dc.subject.emtreeBloodstream infection
dc.subject.emtreeCause of death
dc.subject.emtreeCentral venous catheter
dc.subject.emtreeControlled clinical trial
dc.subject.emtreeControlled study
dc.subject.emtreeEnterobacter cloacae
dc.subject.emtreeEscherichia coli
dc.subject.emtreeFemale
dc.subject.emtreeGram negative infection
dc.subject.emtreeHealthcare associated infection
dc.subject.emtreeHuman
dc.subject.emtreeIntensive care unit
dc.subject.emtreeKlebsiella pneumoniae
dc.subject.emtreeMajor clinical study
dc.subject.emtreeMale
dc.subject.emtreeMortality
dc.subject.emtreeMortality rate
dc.subject.emtreeMulticenter study
dc.subject.emtreeNonhuman
dc.subject.emtreePseudomonas aeruginosa
dc.subject.emtreeRetrospective study
dc.subject.emtreeTurkey (republic)
dc.subject.emtreeVentilator associated pneumonia
dc.subject.emtreeAged
dc.subject.emtreeAntibiotic resistance
dc.subject.emtreeBacteremia
dc.subject.emtreeClassification
dc.subject.emtreeClinical trial
dc.subject.emtreeCross infection
dc.subject.emtreeDrug effects
dc.subject.emtreeGram negative bacterium
dc.subject.emtreeGram-negative bacterial infections
dc.subject.emtreeIsolation and purification
dc.subject.emtreeMicrobiology
dc.subject.emtreeMiddle aged
dc.subject.emtreePrevalence
dc.subject.emtreePrognosis
dc.subject.emtreeRisk factor
dc.subject.emtreeSurvival analysis
dc.subject.emtreeTurkey
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshBacteremia
dc.subject.meshCross infection
dc.subject.meshDrug resistance, bacterial
dc.subject.meshFemale
dc.subject.meshGram-negative bacteria
dc.subject.meshGram-negative bacterial infections
dc.subject.meshHumans
dc.subject.meshIntensive care units
dc.subject.meshMale
dc.subject.meshMiddle aged
dc.subject.meshPrevalence
dc.subject.meshPrognosis
dc.subject.meshRetrospective studies
dc.subject.meshRisk factors
dc.subject.meshSurvival analysis
dc.subject.meshTurkey
dc.subject.scopusBeta-Lactamases; Carbapenem-Resistant Enterobacteriaceae; Klebsiella Pneumoniae
dc.subject.wosPublic, environmental & occupational health
dc.subject.wosInfectious diseases
dc.titleHealthcare-associated Gram-negative bloodstream infections: Antibiotic resistance and predictors of mortality
dc.typeArticle
dc.wos.quartileQ2
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

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