Publication:
In vitro evaluation of electrospun polysaccharide based nanofibrous mats as surgical adhesion barriers

dc.contributor.authorŞafak, Şerife
dc.contributor.buuauthorVatan, Özgür
dc.contributor.buuauthorVATAN, ÖZGÜR
dc.contributor.buuauthorCinkılıç, Nilufer
dc.contributor.buuauthorÇİNKILIÇ, NİLÜFER
dc.contributor.buuauthorKaraca, Esra
dc.contributor.buuauthorKARACA, ESRA
dc.contributor.departmentBursa Uludağ Üniversitesi/Fen Edebiyat Fakültesi/Tekstil Anabilim Dalı.
dc.contributor.orcid0000-0002-7687-3284
dc.contributor.orcid0000-0002-3595-6286
dc.contributor.orcid0000-0003-1777-3977
dc.contributor.researcheridAAH-5296-2021
dc.contributor.researcheridO-7508-2015
dc.contributor.researcheridAAS-8480-2020
dc.contributor.researcheridISV-0209-2023
dc.date.accessioned2024-07-05T06:17:42Z
dc.date.available2024-07-05T06:17:42Z
dc.date.issued2020-01-01
dc.description.abstractPost-operative adhesions are one of the most important problems faced by patients and surgeons. In this study, nanofibrous mats were produced as novel surgical adhesion barrier from polysaccharide-based polymers, hyaluronic acid, carboxymethyl cellulose and sodium alginate, via electrospinning. The produced nanofibrous mats were crosslinked with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride and N-hydroxysulfosuccinimide. Furthermore, the morphology, in vitro degradation, cytotoxicity and cell adherence potentials of the nanofibrous mats aimed to be used as adhesion barriers were evaluated and compared with a commercial adhesion barrier. Results of the in vitro experiment showed that the nanofibrous mats have maintained their physical structures during the critical period for adhesion formation, and had non-adherent cell feature and non-cytotoxic nature required for an ideal adhesion barrier.
dc.identifier.doi10.32710/tekstilvekonfeksiyon.548460
dc.identifier.endpage107
dc.identifier.issn1300-3356
dc.identifier.issue2
dc.identifier.startpage99
dc.identifier.urihttps://doi.org/10.32710/tekstilvekonfeksiyon.548460
dc.identifier.urihttps://hdl.handle.net/11452/42942
dc.identifier.volume30
dc.identifier.wos000576363800003
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherEge Univ
dc.relation.journalTekstil ve Konfeksiyon
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.relation.tubitak214M415
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectHyaluronic-acid
dc.subjectPrevention
dc.subjectMembranes
dc.subjectHydrogels
dc.subjectDelivery
dc.subjectNanofiber
dc.subjectAdhesion barrier
dc.subjectPolysaccharide polymers
dc.subjectIn vitro
dc.subjectScience & technology
dc.subjectTechnology
dc.subjectMaterials science, textiles
dc.subjectMaterials science
dc.titleIn vitro evaluation of electrospun polysaccharide based nanofibrous mats as surgical adhesion barriers
dc.typeArticle
dspace.entity.typePublication
relation.isAuthorOfPublication1de6fd1a-3db1-46bc-9a57-31cc24b984ad
relation.isAuthorOfPublicationbf4540be-dd90-4665-8207-1507eec6f1f0
relation.isAuthorOfPublication4ece70c9-8b96-4a7f-a755-25022ef3b32d
relation.isAuthorOfPublication.latestForDiscovery1de6fd1a-3db1-46bc-9a57-31cc24b984ad

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