Publication: In vitro evaluation of electrospun polysaccharide based nanofibrous mats as surgical adhesion barriers
dc.contributor.author | Şafak, Şerife | |
dc.contributor.buuauthor | Vatan, Özgür | |
dc.contributor.buuauthor | VATAN, ÖZGÜR | |
dc.contributor.buuauthor | Cinkılıç, Nilufer | |
dc.contributor.buuauthor | ÇİNKILIÇ, NİLÜFER | |
dc.contributor.buuauthor | Karaca, Esra | |
dc.contributor.buuauthor | KARACA, ESRA | |
dc.contributor.department | Bursa Uludağ Üniversitesi/Fen Edebiyat Fakültesi/Tekstil Anabilim Dalı. | |
dc.contributor.orcid | 0000-0002-7687-3284 | |
dc.contributor.orcid | 0000-0002-3595-6286 | |
dc.contributor.orcid | 0000-0003-1777-3977 | |
dc.contributor.researcherid | AAH-5296-2021 | |
dc.contributor.researcherid | O-7508-2015 | |
dc.contributor.researcherid | AAS-8480-2020 | |
dc.contributor.researcherid | ISV-0209-2023 | |
dc.date.accessioned | 2024-07-05T06:17:42Z | |
dc.date.available | 2024-07-05T06:17:42Z | |
dc.date.issued | 2020-01-01 | |
dc.description.abstract | Post-operative adhesions are one of the most important problems faced by patients and surgeons. In this study, nanofibrous mats were produced as novel surgical adhesion barrier from polysaccharide-based polymers, hyaluronic acid, carboxymethyl cellulose and sodium alginate, via electrospinning. The produced nanofibrous mats were crosslinked with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride and N-hydroxysulfosuccinimide. Furthermore, the morphology, in vitro degradation, cytotoxicity and cell adherence potentials of the nanofibrous mats aimed to be used as adhesion barriers were evaluated and compared with a commercial adhesion barrier. Results of the in vitro experiment showed that the nanofibrous mats have maintained their physical structures during the critical period for adhesion formation, and had non-adherent cell feature and non-cytotoxic nature required for an ideal adhesion barrier. | |
dc.identifier.doi | 10.32710/tekstilvekonfeksiyon.548460 | |
dc.identifier.endpage | 107 | |
dc.identifier.issn | 1300-3356 | |
dc.identifier.issue | 2 | |
dc.identifier.startpage | 99 | |
dc.identifier.uri | https://doi.org/10.32710/tekstilvekonfeksiyon.548460 | |
dc.identifier.uri | https://hdl.handle.net/11452/42942 | |
dc.identifier.volume | 30 | |
dc.identifier.wos | 000576363800003 | |
dc.indexed.wos | WOS.SCI | |
dc.language.iso | en | |
dc.publisher | Ege Univ | |
dc.relation.journal | Tekstil ve Konfeksiyon | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | |
dc.relation.tubitak | 214M415 | |
dc.rights | info:eu-repo/semantics/closedAccess | |
dc.subject | Hyaluronic-acid | |
dc.subject | Prevention | |
dc.subject | Membranes | |
dc.subject | Hydrogels | |
dc.subject | Delivery | |
dc.subject | Nanofiber | |
dc.subject | Adhesion barrier | |
dc.subject | Polysaccharide polymers | |
dc.subject | In vitro | |
dc.subject | Science & technology | |
dc.subject | Technology | |
dc.subject | Materials science, textiles | |
dc.subject | Materials science | |
dc.title | In vitro evaluation of electrospun polysaccharide based nanofibrous mats as surgical adhesion barriers | |
dc.type | Article | |
dspace.entity.type | Publication | |
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relation.isAuthorOfPublication | 4ece70c9-8b96-4a7f-a755-25022ef3b32d | |
relation.isAuthorOfPublication.latestForDiscovery | 1de6fd1a-3db1-46bc-9a57-31cc24b984ad |