Regio and diastereoselective addition of imidazoline 3-oxides to aryl isocyanates

Abstract

Delta(3)-Imidazoline 3-oxides 1 underwent regio and diastereoselective cycloaddition with aryl isocyanates 2 to give 5,6,7,7a-tetrahydroimidazo[1,5-(b) under bar][1,2,4]oxadiazol-2(1 (H) under bar)-ones 3 in excellent yields. Thermally and chemically induced retro cycloaddition of compounds 3 was demonstrated.