Yayın: Syndecan-1 (CD138) expression in acute myeloblastic leukemia cells - An immuno electron microscopic study
Dosyalar
Tarih
Kurum Yazarları
Çavuşoğlu, İlkin
Yazarlar
Şeftalioğlu, Aysel
Karakuş, Sema
Dündar, Semra
Can, Belgin
Erdemli, Esra
Irmak, Mehmet Kemal
Öztaş, Emin
Korkmaz, Cem
Yazar, Fatih
Danışman
Dil
Türü
Yayıncı:
Taylor and Francis
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Özet
Syndecan-1 (CD138), an important transmembrane heparan sulfate proteoglycan is expressed in distinct stages of cell differentiation. Although its expression in acute lymphoblastic leukemia (ALL) cells is well known; its function or presence in acute myeloblastic leukemia (AML) cells is still largely unknown. The expression of syndecan-1 was studied in bone marrow biopsies of three patients with AML using electron microscopic immunocytochemistry. Positive expression of syndecan-1 was found in AML cells. These results suggest that syndecan-1 expression is not only a characteristic phenotypic marker for ALL, but is also expressed in AML cells.
Açıklama
Kaynak:
Anahtar Kelimeler:
Konusu
Oncology, Heparan-sulfate proteoglycan, Acute lymphoblastic-leukemia, Bone-marrow, Stroma, Molecular-cloning, Migration, Adhesion, Biopsy, Bone, Cells, Electron microscopy, Myeloblastic leukemia cells, Tumors
Alıntı
Şeftalioğlu, A. vd. (2003). “Syndecan-1 (CD138) expression in acute myeloblastic leukemia cells - An immuno electron microscopic study”. Acta Oncologica, 42(1), 71-74.