Publication:
Kainic acid activates oxytocinergic neurons through non-NMDA glutamate receptors

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dc.contributor.buuauthorMinbay, Fatma Zehra
dc.contributor.buuauthorEyigör, Özhan
dc.contributor.buuauthorÇavuşoğlu, İlkin
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentHistoloji ve Embriyoloji Ana Bilim Dalı
dc.contributor.orcid0000-0001-5757-8450
dc.contributor.orcid0000-0003-3463-7483
dc.contributor.researcheridABE-5128-2020
dc.contributor.researcheridABC-1475-2020
dc.contributor.scopusid8220935200
dc.contributor.scopusid6603109907
dc.contributor.scopusid56009155800
dc.date.accessioned2021-12-14T05:35:05Z
dc.date.available2021-12-14T05:35:05Z
dc.date.issued2006
dc.description.abstractThe present study assessed if kainic acid activates oxytocinergic neurons and this activation is blocked by 6- cyano- 7- nitroquinoxaline- 2,3- dione ( CNQX). Dual immunohistochemistry for oxytocin and c- Fos showed that oxytocin neurons in SON and PVN express c- Fos following kainic acid administration, a significant increase when compared to the control group. Administration of CNQX prior to kainic acid caused a significant reduction. The results suggested the participation of non- NMDA receptors in the regulation of oxytocin neurons because the administration of kainic acid activates these neurons and this activation is blocked by CNQX administration.
dc.identifier.citationMinbay, F. Z. vd. (2006). ''Kainic acid activates oxytocinergic neurons through non-NMDA glutamate receptors''. International Journal of Neuroscience, 116(5), 587-600.
dc.identifier.endpage600
dc.identifier.issn0020-7454
dc.identifier.issn1563-5279
dc.identifier.issue5
dc.identifier.pubmed16644519
dc.identifier.scopus2-s2.0-33646472929
dc.identifier.startpage587
dc.identifier.urihttps://doi.org/10.1080/00207450600592123
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.1080/00207450600592123
dc.identifier.urihttp://hdl.handle.net/11452/23219
dc.identifier.volume116
dc.identifier.wos000237489900005
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherTaylor & Francis
dc.relation.journalInternational Journal of Neuroscience
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectNeurosciences & neurology
dc.subjectSON
dc.subjectPVN
dc.subjectOxytocin
dc.subjectKainate
dc.subjectImmunohistochemistry
dc.subjectCNQX
dc.subjectExpression
dc.subjectIn-vitro
dc.subjectLactating rat
dc.subjectSynaptic currents
dc.subjectMagnocellular neurons
dc.subjectSupraoptic nucleus
dc.subjectRat hypothalamus
dc.subjectSubunit messenger-rnas
dc.subjectHypothalamic paraventricular nucleus
dc.subjectMethyl-D-aspartate
dc.subject.emtreeProtein c fos
dc.subject.emtreeOxytocin receptor
dc.subject.emtreeKainic acid
dc.subject.emtreeGlutamate receptor
dc.subject.emtree6 cyano 7 nitro 2,3 quinoxalinedione
dc.subject.emtreeOxytocin
dc.subject.emtreeThalamus midline nucleus
dc.subject.emtreeSupraoptic nucleus
dc.subject.emtreeRegulatory mechanism
dc.subject.emtreeReceptor upregulation
dc.subject.emtreeRat
dc.subject.emtreeProtein expression
dc.subject.emtreeNonhuman
dc.subject.emtreeNerve cell stimulation
dc.subject.emtreeImmunohistochemistry
dc.subject.emtreeFemale
dc.subject.emtreeControlled study
dc.subject.emtreeArticle
dc.subject.emtreeAnimal tissue
dc.subject.meshSupraoptic nucleus
dc.subject.meshReceptors, glutamate
dc.subject.meshRats, sprague-dawley
dc.subject.meshRats
dc.subject.meshProto-oncogene proteins c-fos
dc.subject.meshParaventricular hypothalamic nucleus
dc.subject.meshOxytocin
dc.subject.meshNeurons
dc.subject.meshKainic acid
dc.subject.meshImmunohistochemistry
dc.subject.meshFemale
dc.subject.meshExcitatory amino acid antagonists
dc.subject.meshExcitatory amino acid agonists
dc.subject.meshDrug interactions
dc.subject.meshCell count
dc.subject.meshAnimals
dc.subject.meshAnalysis of variance
dc.subject.mesh6-Cyano-7-nitroquinoxaline-2,3-dione
dc.subject.scopusSupraoptic Nucleus; Magnocellular; Vasopressins
dc.subject.wosNeurosciences
dc.titleKainic acid activates oxytocinergic neurons through non-NMDA glutamate receptors
dc.typeArticle
dc.wos.quartileQ4
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Histoloji ve Embriyoloji Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

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