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Cathecol-O-methyl transferase Val158Met genotype is not a risk factor for conversion disorder

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dc.contributor.authorAlmacıoğlu, M. L.
dc.contributor.buuauthorArmaǧan, Erol
dc.contributor.buuauthorYakut, Tahsin
dc.contributor.buuauthorKöse, Ataman
dc.contributor.buuauthorKarkucak, Mutlu
dc.contributor.buuauthorKöksal, Özlem
dc.contributor.buuauthorGörükmez, Orhan
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıbbi Genetik Ana Bilim Dalı
dc.contributor.orcid0000-0003-2271-5659tr_TR
dc.contributor.researcheridL-7334-2015tr_TR
dc.contributor.researcheridAAM-7896-2020tr_TR
dc.contributor.researcheridAAH-8846-2021tr_TR
dc.contributor.researcheridABI-5648-2022tr_TR
dc.contributor.researcheridAAK-8332-2020tr_TR
dc.contributor.scopusid6506464232tr_TR
dc.contributor.scopusid6602802424tr_TR
dc.contributor.scopusid15755792500tr_TR
dc.contributor.scopusid35388323500tr_TR
dc.contributor.scopusid23389880200tr_TR
dc.contributor.scopusid56681045900tr_TR
dc.date.accessioned2024-01-09T06:35:41Z
dc.date.available2024-01-09T06:35:41Z
dc.date.issued2013
dc.description.abstractAlterations in catechol-O-methyltransferase (COMT) activity are involved in various types of neurological disorders. We examined a possible association between the COMT Val158Met polymorphism and conversion disorder in a study of 48 patients with conversion disorder and 48 control patients. In the conversion disorder group, 31 patients were Val/Met heterozygotes, 15 patients were Val/Val homozygotes and 2 patients were Met/Met homozygotes. In the control group, 32 patients were Val/Met heterozygotes and 16 patients were Val/Val homozygotes. There was no significant difference between the groups. We conclude that the COMT Val158Met genotype is quite common in Turkey and that it is not a risk factor for conversion disorder in the Turkish population.en_US
dc.identifier.citationArmağan, E. (2013). “Cathecol-O-methyl transferase Val158Met genotype is not a risk factor for conversion disorder”. Genetics and Molecular Research, 12(1), 852-858.tr_TR
dc.identifier.endpage858tr_TR
dc.identifier.issn1676-5680
dc.identifier.issue1tr_TR
dc.identifier.pubmed23613193tr_TR
dc.identifier.scopus2-s2.0-84884403737tr_TR
dc.identifier.startpage852tr_TR
dc.identifier.urihttps://doi.org/10.4238/2013.March.19.1
dc.identifier.urihttps://hdl.handle.net/11452/38862
dc.identifier.volume12tr_TR
dc.identifier.wos000318864400092
dc.indexed.pubmedPubMeden_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherFunpec-Editoraen_US
dc.relation.collaborationSanayi işbirliğitr_TR
dc.relation.journalGenetics and Molecular Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiochemistry & molecular biologyen_US
dc.subjectGenetics & heredityen_US
dc.subjectCOMTen_US
dc.subjectVal158Met genotypeen_US
dc.subjectConversion disorderen_US
dc.subjectMethyltransferase geneen_US
dc.subjectBipolar disorderen_US
dc.subjectConduct disorderen_US
dc.subjectEnzyme-activityen_US
dc.subjectCatecholen_US
dc.subjectPolymorphismen_US
dc.subjectAssociationen_US
dc.subjectAttentionen_US
dc.subjectAdhden_US
dc.subject.emtreeCatechol methyltransferaseen_US
dc.subject.emtreeCatechol methyltransferaseen_US
dc.subject.emtreeAdolescenten_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeConversion disorderen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeGenetic associationen_US
dc.subject.emtreeGenetic polymorphismen_US
dc.subject.emtreeGenetic risken_US
dc.subject.emtreeGenotypeen_US
dc.subject.emtreeHeterozygoteen_US
dc.subject.emtreeHomozygoteen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeTurkey (republic)en_US
dc.subject.emtreeAmino acid substitutionen_US
dc.subject.emtreeChi square distributionen_US
dc.subject.emtreeEnzymologyen_US
dc.subject.emtreeGene frequencyen_US
dc.subject.emtreeGenetic polymorphismen_US
dc.subject.emtreeGenetic predispositionen_US
dc.subject.emtreeGeneticsen_US
dc.subject.emtreeMiddle ageden_US
dc.subject.emtreeRisk factoren_US
dc.subject.emtreeVery elderlyen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshAmino acid substitutionen_US
dc.subject.meshCatechol o-methyltransferaseen_US
dc.subject.meshChi-square distributionen_US
dc.subject.meshConversion disorderen_US
dc.subject.meshFemaleen_US
dc.subject.meshGene frequencyen_US
dc.subject.meshGenetic predisposition to diseaseen_US
dc.subject.meshGenotypeen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshPolymorphism, geneticen_US
dc.subject.meshRisk factorsen_US
dc.subject.meshTurkeyen_US
dc.subject.meshYoung adulten_US
dc.subject.scopusCatechol Methyltransferase; Homozygote; Polymorphismen_US
dc.subject.wosBiochemistry & molecular biologyen_US
dc.subject.wosGenetics & heredityen_US
dc.titleCathecol-O-methyl transferase Val158Met genotype is not a risk factor for conversion disorderen_US
dc.typeArticleen_US
dc.wos.quartileQ4en_US
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Acil Tıp Ana Bilim Dalıtr_TR
local.contributor.departmentTıp Fakültesi/Tıbbi Genetik Ana Bilim Dalıtr_TR

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