Publication: Lack of prognostic significance of adiponectin immunohistochemical expression in patients with triplenegative breast cancer
dc.contributor.author | Çubukçu, Erdem | |
dc.contributor.author | Ölmez, Ömer Fatih | |
dc.contributor.author | Kanat, Özkan | |
dc.contributor.author | Kabul, Selva | |
dc.contributor.author | Canhoroz, Mustafa | |
dc.contributor.author | Avcı, Nilüfer | |
dc.contributor.author | Hartavi, Mustafa | |
dc.contributor.author | Deligönül, Adem | |
dc.contributor.author | Çubukçu, Sinem | |
dc.contributor.author | Manavoğlu, Osman | |
dc.contributor.buuauthor | ÇUBUKÇU, ERDEM | |
dc.contributor.buuauthor | Ölmez, Ömer Fatih | |
dc.contributor.buuauthor | Kanat, Özkan | |
dc.contributor.buuauthor | KABUL, SELVA | |
dc.contributor.buuauthor | Canhoroz, Mustafa | |
dc.contributor.buuauthor | Avcı, Nilüfer | |
dc.contributor.buuauthor | Hartavi, Mustafa | |
dc.contributor.buuauthor | DELİGÖNÜL, ADEM | |
dc.contributor.buuauthor | ÇUBUKÇU, SİNEM | |
dc.contributor.buuauthor | Manavoğlu, Osman | |
dc.contributor.department | Tıp Fakültesi | |
dc.contributor.department | İç Hastalıkları Ana Bilim Dalı | |
dc.contributor.researcherid | ETP-1691-2022 | |
dc.contributor.researcherid | DJG-4827-2022 | |
dc.contributor.researcherid | CYM-0930-2022 | |
dc.contributor.researcherid | CAH-9737-2022 | |
dc.contributor.researcherid | CJW-6018-2022 | |
dc.contributor.researcherid | CCT-7946-2022 | |
dc.contributor.researcherid | CUI-5353-2022 | |
dc.contributor.researcherid | ESM-4544-2022 | |
dc.contributor.researcherid | JJB-0254-2023 | |
dc.contributor.researcherid | FLP-9613-2022 | |
dc.date.accessioned | 2024-11-21T11:23:04Z | |
dc.date.available | 2024-11-21T11:23:04Z | |
dc.date.issued | 2014-01-01 | |
dc.description.abstract | Introduction: Triple-negative breast cancers (TNBCs) -which lack the expression of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER-2)-have no established markers that can be used for prognostic stratification. As adiponectin has been previously implicated in a more aggressive phenotype of primary breast cancer, we explored the relation between adiponectin immunohistochemical expression and prognosis in TNBCs.Material and methods: Immunohistochemical staining for adiponectin was performed in 38 TNBC patients. Disease-free survival (DFS) and overall survival (OS) served as the main outcome measures.Results: Of the 38 TNBC patients, 18 (47%) had negative and 20 (53%) positive adiponectin immunohistochemical expression. We did not find any significant association between adipo-nectin immunohistochemical expression and the baseline characteristics. In addition, there were no associations between adiponectin immunohistochemical expression and prognosis.Conclusions: Although our results suggest that adiponectin immunohistochemical expression is not of prognostic significance in TNBCs, further studies are warranted to determine the role of this adipokine in breast cancer biology. | |
dc.identifier.doi | 10.5114/wo.2014.40454 | |
dc.identifier.endpage | 38 | |
dc.identifier.issn | 1428-2526 | |
dc.identifier.issue | 1 | |
dc.identifier.startpage | 34 | |
dc.identifier.uri | https://doi.org/10.5114/wo.2014.40454 | |
dc.identifier.uri | https://www.termedia.pl/Lack-of-prognostic-significance-of-adiponectin-immunohistochemical-expression-in-patients-with-triple-negative-breast-cancer,3,22210,0,1.html | |
dc.identifier.uri | https://hdl.handle.net/11452/48286 | |
dc.identifier.volume | 18 | |
dc.identifier.wos | 000422070400006 | |
dc.indexed.wos | WOS.ESCI | |
dc.language.iso | en | |
dc.publisher | Termedia Publishing House Ltd | |
dc.relation.journal | Wspolczesna Onkologia-Contemporary Oncology | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Triple-negative breast cancer | |
dc.subject | Adiponectin | |
dc.subject | Immunohistochemistry | |
dc.subject | Prognosis | |
dc.subject | Oncology | |
dc.title | Lack of prognostic significance of adiponectin immunohistochemical expression in patients with triplenegative breast cancer | |
dc.type | Article | |
dspace.entity.type | Publication | |
local.contributor.department | Tıp Fakültesi/Tıbbi Onkoloji Ana Bilim Dalı | |
local.contributor.department | Tıp Fakültesi/Patoloji Ana Bilim Dalı | |
local.contributor.department | Tıp Fakültesi/İç Hastalıkları Ana Bilim Dalı | |
relation.isAuthorOfPublication | f971677f-09c5-4463-bf01-3c6341fbe5f7 | |
relation.isAuthorOfPublication | 76775155-c27b-4421-bb7b-b154db42aac3 | |
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relation.isAuthorOfPublication | 375ef438-7ff8-4a42-97a4-74096fac117f | |
relation.isAuthorOfPublication.latestForDiscovery | f971677f-09c5-4463-bf01-3c6341fbe5f7 |
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