Publication:
Association of monocyte to HDL cholesterol level with contrast induced nephropathy in STEMI patients treated with primary PCI

dc.contributor.buuauthorSağ, Salim
dc.contributor.buuauthorYıldız, Abdülmecit
dc.contributor.buuauthorAydın, Kaderli Aysel
dc.contributor.buuauthorGül, Bülent Cuma
dc.contributor.buuauthorBedir, Ömer
dc.contributor.buuauthorCeǧilli, Ercan
dc.contributor.buuauthorÖzdemir, Bülent
dc.contributor.buuauthorCan, Fatma Ezgi
dc.contributor.buuauthorAydınlar, Ali
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentBiyoistatistik Ana Bilim Dalı
dc.contributor.departmentKardiyoloji Ana Bilim Dalı
dc.contributor.departmentNefroloji Ana Bilim Dalı
dc.contributor.orcid0000-0002-8974-8837
dc.contributor.orcid0000-0001-8404-8252
dc.contributor.orcid0000-0002-1953-7735
dc.contributor.researcheridAAI-6632-2021
dc.contributor.researcheridAAW-9185-2020
dc.contributor.scopusid12140008100
dc.contributor.scopusid57192158999
dc.contributor.scopusid7801322152
dc.contributor.scopusid57140207000
dc.contributor.scopusid57191868066
dc.contributor.scopusid57144621700
dc.contributor.scopusid7004168959
dc.contributor.scopusid56689608500
dc.contributor.scopusid57192164890
dc.date.accessioned2022-12-28T12:39:52Z
dc.date.available2022-12-28T12:39:52Z
dc.date.issued2016-05-18
dc.description.abstractBackground: Contrast induced nephropathy (CIN) has been proven to be a clinical condition related to adverse cardiovascular outcomes. In recent studies, the monocyte to high density lipoprotein ratio (MHR) has been-postulated as a novel parameter associated with adverse renal and cardiovascular outcomes. In this study we-investigated the association of MHR with CIN in-ST-segment elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (PCI). Methods: Consecutive STEMI patients treated with primary PCI were prospectively recruited. Subjects were categorized into two groups; as patients who developed CIN (CIN+) and patients who did not develop CIN (CIN-) during hospitalization. CIN was defined as either a 25% increase in serum creatinine from baseline or 44.20 mu mol/L increase in absolute value, within 72 h of intravenous contrast administration. Results: A total number of 209 patients were included in the study. Thirty-two patients developed CIN (15.3%). In the CIN (+) patients, monocytes were higher [1.02 (0.83-1.39) vs. 0.69 (0.53-0.90) 109/L, p < 0.01] and HDL cholesterol levels were lower [0.88 (0.78-1.01) vs. 0.98 (0.88-1.14) mmol/L, p < 0.01]. In addition, MHR was significantly higher in the CIN (+) group [1.16 (0.89-2.16) vs. 0.72 (0.53-0.95) 10(9)/mmol, p < 0.01]. In multivariate logistic regression analysis, MHR, Mehran score, AGEF score and CV/eGFR were independently correlated with CIN. Conclusions: Higher MHR levels may predict CIN development after primary PCI in STEMI patients.
dc.identifier.citationSağ, S. vd. (2017). ''Association of monocyte to HDL cholesterol level with contrast induced nephropathy in STEMI patients treated with primary PCI''. Clinical Chemistry and Laboratory Medicine, 55(1), 132-138.
dc.identifier.endpage138
dc.identifier.issn1434-6621
dc.identifier.issue1
dc.identifier.pubmed27331308
dc.identifier.scopus2-s2.0-84998636412
dc.identifier.startpage132
dc.identifier.urihttps://doi.org/10.1515/cclm-2016-0005
dc.identifier.urihttps://www.degruyter.com/document/doi/10.1515/cclm-2016-0005/html
dc.identifier.uri1437-4331
dc.identifier.urihttp://hdl.handle.net/11452/30143
dc.identifier.volume55
dc.identifier.wos000388930700023
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherWalter de Gruyter
dc.relation.journalClinical Chemistry and Laboratory Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectMedical laboratory technology
dc.subjectContrast induced nephropathy
dc.subjectHDL-cholesterol
dc.subjectMonocyte
dc.subjectPercutaneous coronary intervention
dc.subjectAcute kidney injury
dc.subjectHigh-density-lipoprotein
dc.subjectElevation myocardial-infarction
dc.subjectCreatinine clearance ratio
dc.subjectPrimary angioplasty
dc.subjectCardiovascular events
dc.subjectN-acetylcysteine
dc.subjectRenal-function
dc.subjectRisk score
dc.subject.emtreeAcetylsalicylic acid
dc.subject.emtreeClopidogrel
dc.subject.emtreeCreatinine
dc.subject.emtreeHeparin
dc.subject.emtreeHigh density lipoprotein cholesterol
dc.subject.emtreeIohexol
dc.subject.emtreeContrast medium
dc.subject.emtreeHigh density lipoprotein cholesterol
dc.subject.emtreeAdult
dc.subject.emtreeAged
dc.subject.emtreeAGEF score
dc.subject.emtreeArticle
dc.subject.emtreeContrast induced nephropathy
dc.subject.emtreeControlled study
dc.subject.emtreeCoronary angiography
dc.subject.emtreeCoronary stenting
dc.subject.emtreeCorrelation analysis
dc.subject.emtreeCreatinine blood level
dc.subject.emtreeEstimated glomerular filtration rate
dc.subject.emtreeFemale
dc.subject.emtreeHospitalization
dc.subject.emtreeHuman
dc.subject.emtreeLoading drug dose
dc.subject.emtreeMajor clinical study
dc.subject.emtreeMale
dc.subject.emtreeMehran score
dc.subject.emtreeMiddle aged
dc.subject.emtreeMonocyte
dc.subject.emtreeMultivariate logistic regression analysis
dc.subject.emtreePercutaneous coronary intervention
dc.subject.emtreePercutaneous transluminal angioplasty
dc.subject.emtreePriority journal
dc.subject.emtreeProspective study
dc.subject.emtreeScoring system
dc.subject.emtreeST segment elevation myocardial infarction
dc.subject.emtreeBlood
dc.subject.emtreeChemically induced
dc.subject.emtreeCytology
dc.subject.emtreeKidney diseases
dc.subject.emtreeMonocyte
dc.subject.emtreeReceiver operating characteristic
dc.subject.emtreeST elevation myocardial infarction
dc.subject.meshAged
dc.subject.meshCholesterol, HDL
dc.subject.meshContrast media
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshKidney diseases
dc.subject.meshMale
dc.subject.meshMiddle aged
dc.subject.meshMonocytes
dc.subject.meshPercutaneous coronary intervention
dc.subject.meshROC curve
dc.subject.meshST elevation myocardial infarction
dc.subject.scopusContrast Induced Nephropathy; Coronary Angiography; Kidney Diseases
dc.subject.wosMedical laboratory technology
dc.titleAssociation of monocyte to HDL cholesterol level with contrast induced nephropathy in STEMI patients treated with primary PCI
dc.typeArticle
dc.wos.quartileQ1
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Kardiyoloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Nefroloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Biyoistatistik Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

Files

License bundle

Now showing 1 - 1 of 1
Placeholder
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description: