Publication:
Similarities and differences in the mechanism of action of antidepressants

dc.contributor.buuauthorKırlı, Selçuk
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentPsikiyatri Ana Bilim Dalı
dc.contributor.scopusid14019745700
dc.date.accessioned2022-03-25T13:08:43Z
dc.date.available2022-03-25T13:08:43Z
dc.date.issued2009-03
dc.description.abstractConsidering the pathophysiology of depression, we may talk about the alteration of several receptors, enzymes, neurotransmitters or secondary messengers. Current antidepressants are thought to act by restoring these alterations. Despite having different mechanism of actions, antidepressants act on these interconnected systems to increase CREB or BDNF, thus they have a similar effect on the final biological pathway. However, since antidepressants act on different receptors, the time to response and the symptom profile they act on at the beginning of the therapy may differ. Thus it would be rational to consider the symptom profile and desired time to response when choosing among antidepressants with different mechanism of action or switching from one antidepressant to another.
dc.identifier.citationKırlı, S. (2009). "Similarities and differences in the mechanism of action of antidepressants". Klinik Psikofarmakoloji Bülteni, 19(Supplement 1), S86-S89.
dc.identifier.endpageS89
dc.identifier.issn1017-7833
dc.identifier.issueSupplement 1
dc.identifier.scopus2-s2.0-67650763263
dc.identifier.startpageS86
dc.identifier.urihttp://hdl.handle.net/11452/25359
dc.identifier.volume19
dc.identifier.wos000209020900017
dc.indexed.wosSCIE
dc.language.isotr
dc.publisherKüre İletişim Grubu
dc.relation.journalKlinik Psikofarmakoloji Bülteni
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectMAOI
dc.subjectNRI
dc.subjectSNRI
dc.subjectSSRI
dc.subjectTCA
dc.subjectPharmacology & pharmacy
dc.subjectPsychiatry
dc.subject.emtreeAntidepressant agent
dc.subject.emtreeBrain derived neurotrophic factor
dc.subject.emtreeCyclic AMP responsive element binding protein
dc.subject.emtreeDopamine
dc.subject.emtreeMonoamine oxidase inhibitor
dc.subject.emtreeNoradrenalin
dc.subject.emtreeNoradrenalin uptake inhibitor
dc.subject.emtreeSerotonin
dc.subject.emtreeSerotonin 1A receptor
dc.subject.emtreeSerotonin 1B receptor
dc.subject.emtreeSerotonin 2 receptor
dc.subject.emtreeSerotonin uptake inhibitor
dc.subject.emtreeTianeptine
dc.subject.emtreeTricyclic antidepressant agent
dc.subject.emtreeConference paper
dc.subject.emtreeDepression
dc.subject.emtreeDopamine metabolism
dc.subject.emtreeDrug mechanism
dc.subject.emtreePathophysiology
dc.subject.emtreePsychopharmacotherapy
dc.subject.emtreeSynapse
dc.subject.emtreeTreatment response
dc.subject.scopusDesvenlafaxine; Involutional Depression; Antidepressants
dc.subject.wosPharmacology & pharmacy
dc.subject.wosPsychiatry
dc.titleSimilarities and differences in the mechanism of action of antidepressants
dc.typeArticle
dc.wos.quartileQ4
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Psikiyatri Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

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