Publication: Similarities and differences in the mechanism of action of antidepressants
dc.contributor.buuauthor | Kırlı, Selçuk | |
dc.contributor.department | Tıp Fakültesi | |
dc.contributor.department | Psikiyatri Ana Bilim Dalı | |
dc.contributor.scopusid | 14019745700 | |
dc.date.accessioned | 2022-03-25T13:08:43Z | |
dc.date.available | 2022-03-25T13:08:43Z | |
dc.date.issued | 2009-03 | |
dc.description.abstract | Considering the pathophysiology of depression, we may talk about the alteration of several receptors, enzymes, neurotransmitters or secondary messengers. Current antidepressants are thought to act by restoring these alterations. Despite having different mechanism of actions, antidepressants act on these interconnected systems to increase CREB or BDNF, thus they have a similar effect on the final biological pathway. However, since antidepressants act on different receptors, the time to response and the symptom profile they act on at the beginning of the therapy may differ. Thus it would be rational to consider the symptom profile and desired time to response when choosing among antidepressants with different mechanism of action or switching from one antidepressant to another. | |
dc.identifier.citation | Kırlı, S. (2009). "Similarities and differences in the mechanism of action of antidepressants". Klinik Psikofarmakoloji Bülteni, 19(Supplement 1), S86-S89. | |
dc.identifier.endpage | S89 | |
dc.identifier.issn | 1017-7833 | |
dc.identifier.issue | Supplement 1 | |
dc.identifier.scopus | 2-s2.0-67650763263 | |
dc.identifier.startpage | S86 | |
dc.identifier.uri | http://hdl.handle.net/11452/25359 | |
dc.identifier.volume | 19 | |
dc.identifier.wos | 000209020900017 | |
dc.indexed.wos | SCIE | |
dc.language.iso | tr | |
dc.publisher | Küre İletişim Grubu | |
dc.relation.journal | Klinik Psikofarmakoloji Bülteni | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | |
dc.rights | info:eu-repo/semantics/closedAccess | |
dc.subject | MAOI | |
dc.subject | NRI | |
dc.subject | SNRI | |
dc.subject | SSRI | |
dc.subject | TCA | |
dc.subject | Pharmacology & pharmacy | |
dc.subject | Psychiatry | |
dc.subject.emtree | Antidepressant agent | |
dc.subject.emtree | Brain derived neurotrophic factor | |
dc.subject.emtree | Cyclic AMP responsive element binding protein | |
dc.subject.emtree | Dopamine | |
dc.subject.emtree | Monoamine oxidase inhibitor | |
dc.subject.emtree | Noradrenalin | |
dc.subject.emtree | Noradrenalin uptake inhibitor | |
dc.subject.emtree | Serotonin | |
dc.subject.emtree | Serotonin 1A receptor | |
dc.subject.emtree | Serotonin 1B receptor | |
dc.subject.emtree | Serotonin 2 receptor | |
dc.subject.emtree | Serotonin uptake inhibitor | |
dc.subject.emtree | Tianeptine | |
dc.subject.emtree | Tricyclic antidepressant agent | |
dc.subject.emtree | Conference paper | |
dc.subject.emtree | Depression | |
dc.subject.emtree | Dopamine metabolism | |
dc.subject.emtree | Drug mechanism | |
dc.subject.emtree | Pathophysiology | |
dc.subject.emtree | Psychopharmacotherapy | |
dc.subject.emtree | Synapse | |
dc.subject.emtree | Treatment response | |
dc.subject.scopus | Desvenlafaxine; Involutional Depression; Antidepressants | |
dc.subject.wos | Pharmacology & pharmacy | |
dc.subject.wos | Psychiatry | |
dc.title | Similarities and differences in the mechanism of action of antidepressants | |
dc.type | Article | |
dc.wos.quartile | Q4 | |
dspace.entity.type | Publication | |
local.contributor.department | Tıp Fakültesi/Psikiyatri Ana Bilim Dalı | |
local.indexed.at | Scopus | |
local.indexed.at | WOS |
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