Publication:
Effect of omega-3 polyunsaturated fatty acid supplementation on glycemic control and renal function in type 2 diabetic patients with chronic kidney disease

dc.contributor.authorUsta, Mehmet
dc.contributor.authorAyar, Yavuz
dc.contributor.authorGöksel, Gültekin
dc.contributor.authorKaragöz, İsminur Saka
dc.contributor.buuauthorErsoy, Alparslan
dc.contributor.buuauthorErsoy, Canan
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentNefroloji Ana Bilim Dalı
dc.contributor.departmentEndokrinoloji ve Metabolizma Ana Bilim Dalı
dc.contributor.orcid0000-0002-0710-0923
dc.contributor.researcheridAAH-5054-2021
dc.contributor.researcheridAAH-8861-2021
dc.contributor.scopusid35612977100
dc.contributor.scopusid6701485882
dc.date.accessioned2023-02-02T07:27:55Z
dc.date.available2023-02-02T07:27:55Z
dc.date.issued2020-01-20
dc.description.abstractIntroduction: The aim of this study was to evaluate the short-term effects of omega-3 polyunsaturated fatty acids (n-3 PUFA) supplementation on glycemic control and renal function in type 2 diabetic patients with chronic kidney disease. Materials and methods: Twenty-five diabetic patients received medication containing 2 g/day n-3 PUFA orally in addition to standard treatments. Their estimated glomerular filtration rates (eGFR) were <80 mL/min/1.73 m(2). Biochemical values were evaluated before and 3 months after treatment. Results: After three months of supplementation, the changes in serum creatinine, uric acid, eGFR and urinary albumin excretion levels did not reach statistical significance. There was no difference between serum glucose, HbAlC and lipid profile values before and after the n-3 PUFA.supplementation in patients. Only serum albumin significantly increased from 4.10 +/- 0.26 to 4.28 +/- 0.31 g/dL (p=0.016), and systolic blood pressure decreased from 121.4 +/- 14.5 to 116 .6 +/- 14.9 mmHg (p=0.001). Conclusion: Short-term n-3 PUFA supplementation did not affect renal function and glycemic control in patients with type 2 diabetes with chronic kidney disease.
dc.identifier.citationUsta, M. vd. (2020). "Effect of omega-3 polyunsaturated fatty acid supplementation on glycemic control and renal function in type 2 diabetic patients with chronic kidney disease". Acta Medica Mediterranea, 36(2), 821-828.
dc.identifier.endpage828
dc.identifier.issn0393-6384
dc.identifier.issn2283-9720
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85083360934
dc.identifier.startpage821
dc.identifier.urihttps://doi.org/10.19193/0393-6384_2020_2_128
dc.identifier.urihttps://www.actamedicamediterranea.com/archive/2020/medica-2/effect-of-omega-3-polyunsaturated-fatty-acid-supplementation-on-glycemic-control-and-renal-function-in-type-2-diabetic-patients-with-chronic-kidney-disease
dc.identifier.urihttp://hdl.handle.net/11452/30789
dc.identifier.volume36
dc.identifier.wos000526121600013
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherCarbone Editore
dc.relation.collaborationSanayi
dc.relation.journalActa Medica Mediterranea
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectType 2 diabetes mellitus
dc.subjectChronic kidney disease
dc.subjectCardiovascular disease
dc.subjectOmega-3 polyunsaturated fatty acids
dc.subjectProteinuria
dc.subjectRenal function
dc.subjectBlood-pressure
dc.subjectOmega-3-fatty-acid supplementation
dc.subjectCardiovascular-disease
dc.subjectInsulin-resistance
dc.subjectIga nephropathy
dc.subjectFish-oil
dc.subjectInflammation
dc.subjectBiomarkers
dc.subjectTrial
dc.subjectGeneral & internal medicine
dc.subject.emtreeAlbumin
dc.subject.emtreeCreatinine
dc.subject.emtreeGlucose
dc.subject.emtreeHemoglobin A1c
dc.subject.emtreeOmega 3 fatty acid
dc.subject.emtreeUric acid
dc.subject.emtreeArticle
dc.subject.emtreeChronic kidney failure
dc.subject.emtreeClinical article
dc.subject.emtreeCreatinine blood level
dc.subject.emtreeEstimated glomerular filtration rate
dc.subject.emtreeFemale
dc.subject.emtreeGlucose blood level
dc.subject.emtreeGlycemic control
dc.subject.emtreeHuman
dc.subject.emtreeKidney function
dc.subject.emtreeLipid fingerprinting
dc.subject.emtreeMale
dc.subject.emtreeNon insulin dependent diabetes mellitus
dc.subject.emtreeSystolic blood pressure
dc.subject.emtreeUric acid blood level
dc.subject.emtreeUrinary excretion
dc.subject.scopusCardiovascular Disease; Omega 3 Fatty Acid; Fish Oils
dc.subject.wosMedicine, general & internal
dc.titleEffect of omega-3 polyunsaturated fatty acid supplementation on glycemic control and renal function in type 2 diabetic patients with chronic kidney disease
dc.typeArticle
dc.wos.quartileQ4
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Nefroloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Endokrinoloji ve Metabolizma Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

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