Yayın:
Can diabetes insipidus be used as a marker for multisystemic and progressive disease in langerhans cell histiocytosis?

Placeholder

Akademik Birimler

Yazarlar

Koca, Nizameddin

Danışman

Dil

Türü

Yayıncı:

Kuwait Medical Assoc

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Özet

Langerhans cell histiocytosis (LCH) is a rare disease with an yearly incidence of nine cases per a million in children and 1-2 cases per a million adults. 68.6% of LCH presented with multisystem involvement. A 40-year-old woman who was admitted to endocrinology outpatient clinic with symptoms of polyuria, polydipsia and headache was diagnosed with diabetes insipidus (DI). Desmopressin treatment was initiated, but six months after therapy, re-evaluation revealed progression in hypophyseal mass. Thoracoscopic biopsy shows LCH with multisystemic involvement. She did not respond clinically to systemic chemotherapy and external radiotherapy and died due to pneumonia.LCH should be taken into consideration in patients diagnosed with DI. DI is almost always the hallmark of hypothalamic pituitary axis involvement and a sign of multisystemic involvement.

Açıklama

Kaynak:

Anahtar Kelimeler:

Konusu

Endocrine disorders, Diabetes insipidus, Langerhans cell histiocytosis, Multisystemic disease, Science & technology, Life sciences & biomedicine, Medicine, general & internal, General & internal medicine

Alıntı

Endorsement

Review

Supplemented By

Referenced By

1

Views

0

Downloads