Publication: Ertapenem plus meropenem combination treatment in carbapenem-resistant Klebsiella pneumoniae bacteremia: An analysis of 53 cases
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Date
2023-10-01
Authors
Authors
Onal, Ugur
Akyol, Deniz
Kaya, Arda
Baskol, Dilsah
Kenanoglu, Buse
Sanlidag, Gamze
Onal, Ayse Uyan
Avsar, Cansu Bulut
Mert, Merve
Memetali, Seichan
Journal Title
Journal ISSN
Volume Title
Publisher
Springer
Abstract
Herein, we aimed to describe the outcomes of patients with blood stream infections due to carbapenem-resistant Klebsiella pneumoniae (CR-Kp) who received ertapenem plus meropenem combination treatment (EMCT). A total of 53 patients with culture proven CR-Kp bacteremia treated with ertapenem + meropenem were included. The patients with secondary bacteremia due to urinary tract infection exhibited a significantly lower 1-month mortality (OMM), particularly in those with microbiological eradication and those with end-of-treatment success. Salvage EMCT resulted in 49% 1-month survival.
Description
Keywords
Therapy, Infections, Double carbapenem therapy, Carbapenem-resistant klebsiella pneumonia, Bacteremia, Science & technology, Life sciences & biomedicine, Infectious diseases, Microbiology, Infectious diseases, Microbiology