Publication: Infliximab therapy in an infant with Netherton Syndrome
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Date
2021-04-22
Authors
Çiçek, Fatih
Çekiç, Şükrü
Kılıç, Sara Şebnem
Journal Title
Journal ISSN
Volume Title
Publisher
Wiley
Abstract
We present a patient with Netherton syndrome and severe skin manifestations treated with infliximab. By 6 months of age, the child had intractable pruritus, scaling, dry skin, and generalized eczematous lesions resistant to conventional therapies for atopic dermatitis. Clinical improvement was observed following the third infusion of infliximab, and by 12 months of age, the skin lesions completely resolved. Infliximab is a promising option for the management of skin inflammation in Netherton syndrome, even in infants.
Description
Keywords
Childhood, Ichthyosis, Nfliximab, Netherton syndrome, Tumor necrosis factor‐, Dermatology, Pediatrics