Publication:
Multiple extracranial metastases from secondary glioblastoma: A case report and review of the literature

dc.contributor.buuauthorTaşkapılıoğlu, Mevlüt Özgür
dc.contributor.buuauthorAktaş, Ulaş
dc.contributor.buuauthorEser Ocak, Pınar
dc.contributor.buuauthorTolunay, Şahsine
dc.contributor.buuauthorBekâr, Ahmet
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentNöroşirürji Ana Bilim Dalı
dc.contributor.departmentPatoloji Ana Bilim Dalı
dc.contributor.orcid0000-0001-5472-9065
dc.contributor.orcid0000-0003-0132-9927
dc.contributor.researcheridAAI-2073-2021
dc.contributor.researcheridAAW-5254-2020
dc.contributor.researcheridABB-8161-2020
dc.contributor.researcheridAAI-1612-2021
dc.contributor.scopusid25936798300
dc.contributor.scopusid55122917500
dc.contributor.scopusid55211742300
dc.contributor.scopusid6602604390
dc.contributor.scopusid6603677218
dc.date.accessioned2022-10-21T07:22:18Z
dc.date.available2022-10-21T07:22:18Z
dc.date.issued2013
dc.description.abstractGlioblastoma represents extreme anaplasia in astrocytic tumors. In spite of this aggressiveness, extracranial metastasis of glioblastoma is very rare and has been documented in only a few patients in the literature. In this article, a 30-year-old woman with secondary glioblastoma associated with extracranial distant metastasis was presented. In September 2008, an intracranial lesion in the left frontal region was diagnosed by magnetic resonance imaging (MRI) after admission to the hospital by headache and seizure and subsequently resected. The histology of the lesion revealed an anaplastic astrocytoma (grade III). Upon recurrence of the tumor 7 months later, the patient underwent a second craniotomy for recurrence tumor resection. The histological diagnosis was glioblastoma. After radiotherapy and chemotherapy, cranial computerized tomography (CT) and whole body scintigraphy revealed metastatic lesions in the right cervical lymph nodes and the left ischium. A neck dissection and parathyroidectomy on the right side was performed. The cytomorphological and histological features of the tumor supported the diagnosis of metastatic glioblastoma.
dc.description.abstractGlioblastom astrositik tümörler içerisinde en fazla anaplaziyi gösterenidir. Bu agresif davranışı yanında ekstrakraniyal metastazları oldukça nadirdir ve literatürde çok az hastada bildirilmiştir. Bu makalede, 30 yaşında sekonder glioblastoma bağlı ekstrakraniyal uzak metastazları bulunan bir bayan hasta sunulmuştur. Eylül 2008 tarihinde baş ağrısı ve nöbet şikayeti ile hastaneye başvuran hastanın çekilen kraniyal manyetik rezonans görüntülemesinde sol frontal bölgede intrakraniyal kitle saptanmıştı. Hasta opere edildi. Patoloji tanısı anaplastik astrositom (grade III)olarak raporlandı. 7 ay sonra rekürrens nedeniyle hasta tekrar opere edildi. Histolojik tanısı glioblastom olarak raporlandı. Radyoterapi ve kemoterapiden sonra çektirilen bilgisayarlı tomografi ve tüm vücut sintigrafisinde sağ servikal lenf nodları ve sol iskiumda metastatik lezyonlar saptandı. Sağ taraflı boyun diseksiyonu ve paratiroidektomi uygulandı. Sitomorfolojik ve histolojik çalışmalar metastatik glioblastomla uyumlu olarak bildirildi.
dc.identifier.citationTaşkapılıoğlu, M. Ö. vd. (2013). "Multiple extracranial metastases from secondary glioblastoma: A case report and review of the literature". Turkish Neurosurgery, 23(6), 824-827.
dc.identifier.endpage827
dc.identifier.issn1019-5149
dc.identifier.issue6
dc.identifier.pubmed24310473
dc.identifier.scopus2-s2.0-84891610880
dc.identifier.startpage824
dc.identifier.urihttps://doi.org/10.5137/1019-5149.JTN.6497-12.1
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/24310473/
dc.identifier.urihttp://hdl.handle.net/11452/29174
dc.identifier.volume23
dc.identifier.wos000329598700024
dc.indexed.scopusScopus
dc.indexed.trdizinTrDizin
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherTürk Nöroloji Derneği
dc.relation.journalTurkish Neurosurgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNeurosciences & neurology
dc.subjectSurgery
dc.subjectGlioblastoma
dc.subjectExtracranial metastasis
dc.subjectSecondary glioblastoma
dc.subjectPrognosis
dc.subjectParotid-gland
dc.subjectMultiforme
dc.subjectGlioblastom
dc.subjectEkstrakraniyal metastaz
dc.subjectSekonder glioblastom
dc.subjectPrognoz
dc.subject.emtreeAdult
dc.subject.emtreeArticle
dc.subject.emtreeBrain tumor
dc.subject.emtreeCase report
dc.subject.emtreeComputer assisted tomography
dc.subject.emtreeFatality
dc.subject.emtreeFemale
dc.subject.emtreeGlioblastoma
dc.subject.emtreeHuman
dc.subject.emtreeLymph node metastasis
dc.subject.emtreeMetastasis
dc.subject.emtreeNeck dissection
dc.subject.emtreeNeurosurgery
dc.subject.emtreeNuclear magnetic resonance imaging
dc.subject.emtreeParotid gland tumor
dc.subject.emtreePathology
dc.subject.emtreePregnancy
dc.subject.emtreeWhole body counting
dc.subject.meshAdult
dc.subject.meshBrain neoplasms
dc.subject.meshFatal outcome
dc.subject.meshFemale
dc.subject.meshGlioblastoma
dc.subject.meshHumans
dc.subject.meshLymphatic metastasis
dc.subject.meshMagnetic resonance imaging
dc.subject.meshNeck dissection
dc.subject.meshNeurosurgical procedures
dc.subject.meshParotid neoplasms
dc.subject.meshPregnancy
dc.subject.meshTomography, x-ray computed
dc.subject.meshWhole-body counting
dc.subject.scopusCase Report; Glioblastoma; Central Nervous System Neoplasms
dc.subject.wosClinical neurology
dc.subject.wosSurgery
dc.titleMultiple extracranial metastases from secondary glioblastoma: A case report and review of the literature
dc.title.alternativeSekonder glioblastomaya bağlı gelişen çoklu ekstrakraniyal metastazlar: Bir olgu sunumu ve literatürün gözden geçirilmesi
dc.typeReview
dc.wos.quartileQ4
dc.wos.quartileQ4
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Nöroşirürji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Patoloji Ana Bilim Dalı
local.indexed.atTrDizin
local.indexed.atWOS
local.indexed.atScopus

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