Publication:
The effects of levobupivacaine infiltration on post-tonsillectomy pain relief in adults: A single-blinded, randomized, and controlled clinical study

dc.contributor.buuauthorKasapoǧlu, Fikret
dc.contributor.buuauthorDemir, Uygar Levent
dc.contributor.buuauthorKaya, Fatma Nur
dc.contributor.buuauthorÇetin, Yaser Said
dc.contributor.buuauthorYavaşçaoǧlu, Belgin
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentKulak Burun Boğaz Ana Bilim Dalı
dc.contributor.departmentAnesteziyoloji ve Reanimasyon Ana Bilim Dalı
dc.contributor.orcid0000-0002-7684-4600
dc.contributor.researcheridAAG-9356-2021
dc.contributor.researcheridAAI-7914-2021
dc.contributor.researcheridAAI-3877-2021
dc.contributor.researcheridAAI-8213-2021
dc.contributor.scopusid56254721200
dc.contributor.scopusid56868421800
dc.contributor.scopusid7003619647
dc.contributor.scopusid57202732676
dc.contributor.scopusid6602742300
dc.date.accessioned2022-10-21T07:00:08Z
dc.date.available2022-10-21T07:00:08Z
dc.date.issued2013-02
dc.description.abstractThe aim of this prospective single-blinded and controlled study is to evaluate the efficacy of levobupivacaine infiltration on post-tonsillectomy pain relief in adults. The study was conducted with 40 adult patients who underwent tonsillectomy. These patients were randomized in either study group (SG) who received levobupivacaine infiltration to peritonsillary fossae prior to surgery or control group (CG) with no medication. After surgery, all the patients were queried for pain scores by visual analog scale. In addition, the volume of intraoperative bleeding, the duration of operation, the severity of postoperative complications, and the amount of analgesic requirement were the other outcome measures of this study. There were significant differences between groups regarding pain scores for the first 24 h in favor of SG. The analgesic requirement was also significantly lower in SG (p = 0.009). Although there was a sustained decrement at pain score during first 24 h for SG, however, the change from baseline score (immediate score) for each time interval revealed no significance compared to CG. In addition, the duration of operation and the volume of intraoperative bleeding were similar (p = 0.64 and p = 0.165). In conclusion, preincisional infiltration of levobupivacaine is a safe and reliable method for post-tonsillectomy pain reduction in adults. However, more in-depth, double-blinded and placebo controlled studies are required to elucidate its long term benefits.
dc.identifier.citationKasapoğlu, F. vd. (2013). "The effects of levobupivacaine infiltration on post-tonsillectomy pain relief in adults: a single-blinded, randomized, and controlled clinical study". European Archives of Oto-Rhino-Laryngology, 270(2), 761-766.
dc.identifier.endpage766
dc.identifier.issn0937-4477
dc.identifier.issn1434-4726
dc.identifier.issue2
dc.identifier.pubmed23053376
dc.identifier.scopus2-s2.0-84878376736
dc.identifier.startpage761
dc.identifier.urihttps://doi.org/10.1007/s00405-012-2194-1
dc.identifier.urihttps://link.springer.com/article/10.1007/s00405-012-2194-1
dc.identifier.urihttp://hdl.handle.net/11452/29173
dc.identifier.volume270
dc.identifier.wos000314295800050
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherSpringer
dc.relation.journalEuropean Archives of Oto-Rhino-Laryngology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectOtorhinolaryngology
dc.subjectAdult
dc.subjectTonsillectomy
dc.subjectPostoperative pain
dc.subjectLevobupivacaine
dc.subjectPediatric tonsillectomy
dc.subjectTopical lidocaine
dc.subjectControlled-trial
dc.subjectBupivacaine
dc.subjectMorbidity
dc.subjectDexamethasone
dc.subjectMetaanalysis
dc.subjectRopivacaine
dc.subjectAnalgesia
dc.subjectTonsils
dc.subject.emtreeLevobupivacaine
dc.subject.emtreeAdult
dc.subject.emtreeAnalgesia
dc.subject.emtreeArticle
dc.subject.emtreeClinical article
dc.subject.emtreeControlled study
dc.subject.emtreeDisease severity
dc.subject.emtreeDrug administration
dc.subject.emtreeDrug effect
dc.subject.emtreeDrug efficacy
dc.subject.emtreeFemale
dc.subject.emtreeHuman
dc.subject.emtreeMale
dc.subject.emtreeOperation duration
dc.subject.emtreeOutcome assessment
dc.subject.emtreePain assessment
dc.subject.emtreePostoperative complication
dc.subject.emtreePostoperative hemorrhage
dc.subject.emtreePostoperative pain
dc.subject.emtreePriority journal
dc.subject.emtreeProspective study
dc.subject.emtreeRandomized controlled trial
dc.subject.emtreeSingle blind procedure
dc.subject.emtreeTonsillectomy
dc.subject.emtreeVisual analog scale
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshAnesthesia, local
dc.subject.meshAnesthetics, local
dc.subject.meshBupivacaine
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle aged
dc.subject.meshPain measurement
dc.subject.meshPain, postoperative
dc.subject.meshSingle-blind method
dc.subject.meshTonsillectomy
dc.subject.meshYoung adult
dc.subject.scopusTonsillectomy; Hemorrhage; Postoperative Hemorrhage
dc.subject.wosOtorhinolaryngology
dc.titleThe effects of levobupivacaine infiltration on post-tonsillectomy pain relief in adults: A single-blinded, randomized, and controlled clinical study
dc.typeArticle
dc.wos.quartileQ2
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Kulak Burun Boğaz Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Anesteziyoloji ve Reanimasyon Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

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