Publication: Vasorelaxant effects of biochemical constituents of various medicinal plants and their benefits in diabetes
dc.contributor.author | Demirel, Sadettin | |
dc.contributor.buuauthor | DEMİREL, SADETTİN | |
dc.contributor.department | Tıp Fakültesi | |
dc.contributor.department | Fizyoloji Anabilim Dalı | |
dc.contributor.researcherid | AAH-3460-2021 | |
dc.date.accessioned | 2025-01-17T05:46:03Z | |
dc.date.available | 2025-01-17T05:46:03Z | |
dc.date.issued | 2024-06-15 | |
dc.description.abstract | Endothelial function plays a pivotal role in cardiovascular health, and dysfunction in this context diminishes vasorelaxation concomitant with endothelial activity. The nitric oxide-cyclic guanosine monophosphate pathway, prostacyclin-cyclic adenosine monophosphate pathway, inhibition of phosphodiesterase, and the opening of potassium channels, coupled with the reduction of calcium levels in the cell, constitute critical mechanisms governing vasorelaxation. Cardiovascular disease stands as a significant contributor to morbidity and mortality among individuals with diabetes, with adults afflicted by diabetes exhibiting a heightened cardiovascular risk compared to their non-diabetic counterparts. A plethora of medicinal plants, characterized by potent pharmacological effects and minimal side effects, holds promise in addressing these concerns. In this review, we delineate various medicinal plants and their respective biochemical constituents, showcasing concurrent vasorelaxant and anti-diabetic activities. | |
dc.identifier.doi | 10.4239/wjd.v15.i6.1122 | |
dc.identifier.eissn | 1948-9358 | |
dc.identifier.issue | 6 | |
dc.identifier.uri | https://doi.org/10.4239/wjd.v15.i6.1122 | |
dc.identifier.uri | https://www.wjgnet.com/1948-9358/full/v15/i6/1122.htm | |
dc.identifier.uri | https://pmc.ncbi.nlm.nih.gov/articles/PMC11229960/ | |
dc.identifier.uri | https://hdl.handle.net/11452/49524 | |
dc.identifier.volume | 15 | |
dc.identifier.wos | 001272220800002 | |
dc.indexed.wos | WOS.SCI | |
dc.language.iso | en | |
dc.publisher | Baishideng Publishing | |
dc.relation.journal | World Journal of Diabetes | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Alpha-glucosidase activity | |
dc.subject | Tyrosine-phosphatase 1b | |
dc.subject | Morus-bombycis koidzumi | |
dc.subject | Artemisia-herba-alba | |
dc.subject | Rat thoracic aorta | |
dc.subject | Nitric-oxide | |
dc.subject | Ethanol extract | |
dc.subject | Leaf extract | |
dc.subject | Vascular relaxation | |
dc.subject | Blood-glucose | |
dc.subject | Medicinal plants | |
dc.subject | Vasorelaxation | |
dc.subject | Endothelium | |
dc.subject | Diabetes | |
dc.subject | Anti-diabetic | |
dc.subject | Science & technology | |
dc.subject | Life sciences & biomedicine | |
dc.subject | Endocrinology & metabolism | |
dc.title | Vasorelaxant effects of biochemical constituents of various medicinal plants and their benefits in diabetes | |
dc.type | Review | |
dspace.entity.type | Publication | |
local.contributor.department | Tıp Fakültesi/Fizyoloji Anabilim Dalı | |
local.indexed.at | WOS | |
relation.isAuthorOfPublication | bf421fa5-e949-4453-b2b2-c4a9df1be392 | |
relation.isAuthorOfPublication.latestForDiscovery | bf421fa5-e949-4453-b2b2-c4a9df1be392 |
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