Publication:
Effects of vitamin d administration at the beginning of lactation in dairy cows on inflammatory response and liver metabolism

dc.contributor.authorKaya, Feyyaz
dc.contributor.authorBatmaz, Hasan
dc.contributor.buuauthorKaya, Feyyaz
dc.contributor.buuauthorBatmaz, Hasan
dc.contributor.buuauthorBATMAZ, HASAN
dc.contributor.departmentVeteriner Fakültesi
dc.contributor.orcid0000-0001-8820-1509
dc.contributor.researcheridIXN-7700-2023
dc.date.accessioned2024-06-28T10:49:23Z
dc.date.available2024-06-28T10:49:23Z
dc.date.issued2021-11-26
dc.description.abstractThis study aimed to investigate the effect of vitamin D administered 24 h after calving of dairy cows on calcium-phosphorus metabolism, carbohydrate, lipid and liver metabolism, and inflammatory response. Twenty multiparous Holstein cows were randomly assigned to the experimental (EG) and control group (CG). The EG received 5,000,000 IU vitamin D 3 (5 mL) 24 h after parturition intramuscularly, whereas the CG group received 5 mL of 0.9% NaCl. Blood samples were taken 24 h after parturition before treatments and at the 3rd, 7th, 14th, and 28th days of lactation. Serum NEFA, BHBA, haptoglobin, serum amyloid A (SAA), ceruloplasmin, calcium, phosphorus, parathormone, total protein, triglyceride, AST, and GGT were measured. In addition, total bilirubin, albumin, total cholesterol, and vitamin A concentrations were also measured to calculate liver activity index and the liver functionality index. Subclinical hypocalcemia (SCH) was observed in only one cow in the EG and five in the CG after the 3rd day postpartum. NEFA levels in the EG significantly differed on days 7, 14, and 28 when compared to vitamin D pretreatment values. However, NEFA levels in the CG differed only between day 28 postpartum and the 1st day (p < 0.05). Negative correlation was determined between vitamin D and NEFA (p < 0.01). Conversely, negative correlations were observed between calcium and NEFA, haptoglobin, SAA (p < 0.05). In conclusion, it can be suggested that vitamin D administration can prevent SCH after the 3rd day and has limited positive effects on postpartum NEFA levels.
dc.identifier.doi10.3906/vet-2107-36
dc.identifier.endpage114
dc.identifier.issn1300-0128
dc.identifier.issue1
dc.identifier.startpage107
dc.identifier.urihttps://doi.org/10.3906/vet-2107-36
dc.identifier.urihttps://hdl.handle.net/11452/42580
dc.identifier.volume46
dc.identifier.wos000756597400001
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherTubitak Scientific & Technological Research Council Turkey
dc.relation.journalTurkish Journal Of Veterinary & Animal Sciences
dc.relation.tubitakTUBİTAK
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAcute-phase proteins
dc.subjectSubclinical hypocalcemia
dc.subjectNeutrophil function
dc.subjectMilk fever
dc.subjectCalcium
dc.subjectHealth
dc.subjectCattle
dc.subjectPeriod
dc.subjectAssociation
dc.subjectPostpartum
dc.subjectDairy cow
dc.subjectVitamin d
dc.subjectCalcium
dc.subjectNefa
dc.subjectLiver metabolism
dc.subjectInflammation
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectVeterinary sciences
dc.subjectVeterinary sciences
dc.titleEffects of vitamin d administration at the beginning of lactation in dairy cows on inflammatory response and liver metabolism
dc.typeArticle
dspace.entity.typePublication
local.contributor.departmentVeteriner Fakültesi
relation.isAuthorOfPublication485139b1-b60e-4e07-a83a-eb553b0a835d
relation.isAuthorOfPublication.latestForDiscovery485139b1-b60e-4e07-a83a-eb553b0a835d

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