Publication: Evaluation of prognostic factors on survival in non-small-cell lung cancer patients treated with postoperative radiotherapy
dc.contributor.buuauthor | Sarıhan, Süreyya | |
dc.contributor.buuauthor | SARIHAN, SÜREYYA | |
dc.contributor.buuauthor | Gebitekin, Cengiz | |
dc.contributor.buuauthor | ERCAN, İLKER | |
dc.contributor.buuauthor | GEBİTEKİN, CENGİZ | |
dc.contributor.buuauthor | Bayram, Ahmet Sami | |
dc.contributor.buuauthor | BAYRAM, AHMET SAMİ | |
dc.contributor.buuauthor | EVRENSEL, TÜRKKAN | |
dc.contributor.buuauthor | Evrensel, Turkkan | |
dc.contributor.buuauthor | Akyıldız, Elif Ülker | |
dc.contributor.buuauthor | AKYILDIZ, ELİF ÜLKER | |
dc.contributor.department | Bursa Uludağ Üniversitesi/Tıp Fakültesi/Radyasyon Onkolojisi Anabilim Dalı. | |
dc.contributor.department | Bursa Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı. | |
dc.contributor.department | Bursa Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı. | |
dc.contributor.department | Bursa Uludağ Üniversitesi/Tıp Fakültesi/Onkoloji Anabilim Dalı. | |
dc.contributor.department | Bursa Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı. | |
dc.contributor.orcid | 0000-0003-4816-5798 | |
dc.contributor.orcid | 0000-0003-0684-0900 | |
dc.contributor.orcid | 0000-0002-2382-290X | |
dc.contributor.researcherid | ABB-7580-2020 | |
dc.contributor.researcherid | AAJ-1027-2021 | |
dc.contributor.researcherid | JCE-0097-2023 | |
dc.contributor.researcherid | AAH-4970-2021 | |
dc.contributor.researcherid | AAE-1069-2022 | |
dc.date.accessioned | 2024-10-01T06:55:37Z | |
dc.date.available | 2024-10-01T06:55:37Z | |
dc.date.issued | 2009-01-01 | |
dc.description.abstract | OBJECTIVESTo investigate the prognostic factors on survival in non-small-cell lung cancer patients treated with postoperative radiotherapy.METHODSSixty-five patients treated with a median dose of 59 Gy (50-66.6 Gy) between October 1995 and January 2005 were included in the study. Clinical and categorical variables were analyzed.RESULTSOn multivariate analysis, presence of clinical N2 and brain metastasis at first relapse and absence of chemotherapy (p=0.02, p=0.004, p=0.004) had a negative impact on overall survival, while presence of pathological nodal involvement and absence of chemotherapy (p=0.02, p=0.04) were effective on disease-free survival. Regarding categorical variables, type of resection was found related with positive margin and N1, right-sided location with N1-e and N2, and systematic nodal dissection with N1. The number of involved lymph nodes was found related with N2 skip metastasis and involved N1-10 was related with N1-e.CONCLUSIONPresence of metastatic lymph nodes was found to be a poor prognostic factor and delivery of chemotherapy was seen to positively affect overall and disease-free survival rates. | |
dc.identifier.endpage | 64 | |
dc.identifier.issn | 1300-7467 | |
dc.identifier.issue | 2 | |
dc.identifier.startpage | 53 | |
dc.identifier.uri | https://hdl.handle.net/11452/45566 | |
dc.identifier.volume | 24 | |
dc.identifier.wos | 000439262300001 | |
dc.indexed.wos | WOS.ESCI | |
dc.language.iso | en | |
dc.publisher | Kare Publ | |
dc.relation.journal | Turk Onkoloji Dergisi-turkish Journal Of Oncology | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | |
dc.subject | Pathological n1 disease | |
dc.subject | Lymph-node dissection | |
dc.subject | Resected stage-ii | |
dc.subject | Randomized-trial | |
dc.subject | Adjuvant radiotherapy | |
dc.subject | 2 cm | |
dc.subject | Carcinoma | |
dc.subject | Therapy | |
dc.subject | Involvement | |
dc.subject | Metastasis | |
dc.subject | Non-small-cell lung cancer | |
dc.subject | Postoperative radiotherapy | |
dc.subject | Prognostic factors | |
dc.subject | Survival | |
dc.subject | Science & technology | |
dc.subject | Life sciences & biomedicine | |
dc.subject | Oncology | |
dc.title | Evaluation of prognostic factors on survival in non-small-cell lung cancer patients treated with postoperative radiotherapy | |
dc.type | Article | |
dspace.entity.type | Publication | |
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