Publication:
Evaluation of prognostic factors on survival in non-small-cell lung cancer patients treated with postoperative radiotherapy

dc.contributor.buuauthorSarıhan, Süreyya
dc.contributor.buuauthorSARIHAN, SÜREYYA
dc.contributor.buuauthorGebitekin, Cengiz
dc.contributor.buuauthorERCAN, İLKER
dc.contributor.buuauthorGEBİTEKİN, CENGİZ
dc.contributor.buuauthorBayram, Ahmet Sami
dc.contributor.buuauthorBAYRAM, AHMET SAMİ
dc.contributor.buuauthorEVRENSEL, TÜRKKAN
dc.contributor.buuauthorEvrensel, Turkkan
dc.contributor.buuauthorAkyıldız, Elif Ülker
dc.contributor.buuauthorAKYILDIZ, ELİF ÜLKER
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Radyasyon Onkolojisi Anabilim Dalı.
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Onkoloji Anabilim Dalı.
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.
dc.contributor.orcid0000-0003-4816-5798
dc.contributor.orcid0000-0003-0684-0900
dc.contributor.orcid0000-0002-2382-290X
dc.contributor.researcheridABB-7580-2020
dc.contributor.researcheridAAJ-1027-2021
dc.contributor.researcheridJCE-0097-2023
dc.contributor.researcheridAAH-4970-2021
dc.contributor.researcheridAAE-1069-2022
dc.date.accessioned2024-10-01T06:55:37Z
dc.date.available2024-10-01T06:55:37Z
dc.date.issued2009-01-01
dc.description.abstractOBJECTIVESTo investigate the prognostic factors on survival in non-small-cell lung cancer patients treated with postoperative radiotherapy.METHODSSixty-five patients treated with a median dose of 59 Gy (50-66.6 Gy) between October 1995 and January 2005 were included in the study. Clinical and categorical variables were analyzed.RESULTSOn multivariate analysis, presence of clinical N2 and brain metastasis at first relapse and absence of chemotherapy (p=0.02, p=0.004, p=0.004) had a negative impact on overall survival, while presence of pathological nodal involvement and absence of chemotherapy (p=0.02, p=0.04) were effective on disease-free survival. Regarding categorical variables, type of resection was found related with positive margin and N1, right-sided location with N1-e and N2, and systematic nodal dissection with N1. The number of involved lymph nodes was found related with N2 skip metastasis and involved N1-10 was related with N1-e.CONCLUSIONPresence of metastatic lymph nodes was found to be a poor prognostic factor and delivery of chemotherapy was seen to positively affect overall and disease-free survival rates.
dc.identifier.endpage64
dc.identifier.issn1300-7467
dc.identifier.issue2
dc.identifier.startpage53
dc.identifier.urihttps://hdl.handle.net/11452/45566
dc.identifier.volume24
dc.identifier.wos000439262300001
dc.indexed.wosWOS.ESCI
dc.language.isoen
dc.publisherKare Publ
dc.relation.journalTurk Onkoloji Dergisi-turkish Journal Of Oncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.subjectPathological n1 disease
dc.subjectLymph-node dissection
dc.subjectResected stage-ii
dc.subjectRandomized-trial
dc.subjectAdjuvant radiotherapy
dc.subject2 cm
dc.subjectCarcinoma
dc.subjectTherapy
dc.subjectInvolvement
dc.subjectMetastasis
dc.subjectNon-small-cell lung cancer
dc.subjectPostoperative radiotherapy
dc.subjectPrognostic factors
dc.subjectSurvival
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectOncology
dc.titleEvaluation of prognostic factors on survival in non-small-cell lung cancer patients treated with postoperative radiotherapy
dc.typeArticle
dspace.entity.typePublication
relation.isAuthorOfPublication07b16629-e65c-40b0-b11d-825ad7943570
relation.isAuthorOfPublication029ec57f-2451-4282-8110-61c87cd6a41d
relation.isAuthorOfPublicationbdb7801d-f0bc-4abc-af2c-5bf7df23fbd5
relation.isAuthorOfPublicationeceff514-6af7-4c3b-a146-b77546565a6c
relation.isAuthorOfPublicationa6528db3-6c7b-4f9f-a03d-e9ad2017907e
relation.isAuthorOfPublication.latestForDiscovery07b16629-e65c-40b0-b11d-825ad7943570

Files

Collections