Publication:
Serum prolactin in neonatal seizures

dc.contributor.buuauthorKılıç, Sara Şebnem
dc.contributor.buuauthorTarım, Ömer
dc.contributor.buuauthorEralp, Özgen
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentPediatri Ana Bilim Dalı
dc.contributor.researcheridAAH-1658-2021
dc.contributor.scopusid34975059200
dc.contributor.scopusid6701427186
dc.contributor.scopusid6603426177
dc.date.accessioned2021-11-17T07:26:40Z
dc.date.available2021-11-17T07:26:40Z
dc.date.issued1999
dc.description.abstractBackground: Prolactin is the most specific neurohormone that is elevated after seizures. This study was undertaken to determine the clinical usefulness of plasma prolactin as a diagnostic aid in differential diagnosis of neonatal convulsions. Methods: Forty-five patients followed for seizures were included in the study. Postictal serum prolactin levels were obtained 30 min after the onset of the seizures. A second sample obtained 24 h later was used to measure an unstimulated serum prolactin level. Results: The most common cause of seizure was hypoxic ischemic encephalopathy (HIE) followed by sepsis. In patients with HIE, postictal serum prolactin levels were significantly higher than the unstimulated levels (P < 0.0002). Additionally, postictal prolactin levels were significantly higher than the unstimulated levels in clonic (P < 0.02) and tonic convulsions (P < 0.001). Conclusions: We conclude that the postictal serum prolactin level may be a marker in the differentiation of seizures as well as providing important information about their etiology. Further studies are needed to assess the normal range of serum prolactin levels in unstressed newborns.
dc.identifier.citationKılıç, S. Ş. vd. (1999). "Serum prolactin in neonatal seizures". Pediatrics International, 41(1), 61-64.
dc.identifier.endpage64
dc.identifier.issn1328-8067
dc.identifier.issue1
dc.identifier.pubmed10200138
dc.identifier.scopus2-s2.0-0033001655
dc.identifier.startpage61
dc.identifier.urihttps://doi.org/10.1046/j.1442-200x.1999.01018.x
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/full/10.1046/j.1442-200x.1999.01018.x
dc.identifier.urihttp://hdl.handle.net/11452/22681
dc.identifier.volume41
dc.identifier.wos000082490400012
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherWiley
dc.relation.journalPediatrics International
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPediatrics
dc.subjectConvulsions
dc.subjectNeonatal
dc.subjectSeizures
dc.subjectProlactin
dc.subjectClassification
dc.subject.emtreeNeurohormone
dc.subject.emtreeProlactin
dc.subject.emtreeArticle
dc.subject.emtreeBrain ischemia
dc.subject.emtreeClinical article
dc.subject.emtreeClonic seizure
dc.subject.emtreeControlled study
dc.subject.emtreeFemale
dc.subject.emtreeHuman
dc.subject.emtreeHypoxia
dc.subject.emtreeMale
dc.subject.emtreeNewborn
dc.subject.emtreeNewborn sepsis
dc.subject.emtreePriority journal
dc.subject.emtreeProlactin blood level
dc.subject.emtreeSeizure
dc.subject.emtreeTonic seizure
dc.subject.meshAnoxia
dc.subject.meshBiological markers
dc.subject.meshCerebral hemorrhage
dc.subject.meshDiagnosis, differential
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshHypocalcemia
dc.subject.meshHypoglycemia
dc.subject.meshInfant, newborn
dc.subject.meshInfection
dc.subject.meshMale
dc.subject.meshProlactin
dc.subject.meshReproducibility of results
dc.subject.meshSeizures
dc.subject.meshTime factors
dc.subject.scopusBenzo(A)Pyrene; Cell Lines; Rats
dc.subject.wosPediatrics
dc.titleSerum prolactin in neonatal seizures
dc.typeArticle
dc.wos.quartileQ4
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Pediatri Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

Files

License bundle

Now showing 1 - 1 of 1
Placeholder
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description: