Publication:
Free choline and phospholipid-bound choline concentrations in serum and dialysate during peritoneal dialysis in children and adults

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dc.contributor.buuauthorİlçol, Yeşim Özarda
dc.contributor.buuauthorDönmez, Osman
dc.contributor.buuauthorYavuz, Mahmut
dc.contributor.buuauthorDilek, Kamil
dc.contributor.buuauthorYurtkuran, Mustafa
dc.contributor.buuauthorUlus, İsmail Hakkı
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentNefroloji Ana Bilim Dalı
dc.contributor.departmentFarmakoloji ve Klinik Farmakoloji Ana Bilim Dalı
dc.contributor.researcheridAAL-8873-2021
dc.contributor.researcheridD-5340-2015
dc.contributor.researcheridAAA-8778-2021
dc.contributor.scopusid35741320500
dc.contributor.scopusid19033971800
dc.contributor.scopusid7006244754
dc.contributor.scopusid56005080200
dc.contributor.scopusid7003389525
dc.contributor.scopusid7004271086
dc.date.accessioned2021-10-23T08:19:52Z
dc.date.available2021-10-23T08:19:52Z
dc.date.issued2002-07
dc.description.abstractObjectives: This study tested whether continuous ambulatory peritoneal dialysis (CAPD) changes free or phospholipid-bound choline concentrations in serum or peritoneal dialysis fluid of patients with end stage renal disease (ESRD). Design and methods: Serum and dialysate choline and phospholipid-bound choline were measured before, during and after 6 h CAPD. Results: Serum choline concentrations were higher in patients with ESRD compared with age-matched controls. CAPD lowered serum choline concentrations significantly although it did not influence phospholipid-bound choline. Choline accumulated in the dialysate, reaching 28.4 +/- 2.7 muM in children and 18.2 +/- 1.4 muM in adults, during six hours CAPD; phospholipid-bound choline increased to 22.9 +/- 2.5 muM and 10.8 +/- 1.4 muM in children and adults, respectively. The total daily loss of choline into the dialysate was 181 +/- 20 mumoles in children and 260 +/- 18 mumoles in adults. Conclusion: CAPD causes a substantial loss of choline into peritoneal dialysates and reduces serum choline concentrations significantly.
dc.identifier.citationÖzarda, Y. vd. (2002). "Free choline and phospholipid-bound choline concentrations in serum and dialysate during peritoneal dialysis in children and adults". Clinical Biochemistry, 35(4), 307-313.
dc.identifier.endpage313
dc.identifier.issn0009-9120
dc.identifier.issue4
dc.identifier.pubmed12135694
dc.identifier.scopus2-s2.0-0035992614
dc.identifier.startpage307
dc.identifier.urihttps://doi.org/10.1016/S0009-9120(02)00319-3
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0009912002003193
dc.identifier.urihttp://hdl.handle.net/11452/22452
dc.identifier.volume35
dc.identifier.wos000177355800010
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherPergamon-Elsevier Science
dc.relation.journalClinical Biochemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCholine
dc.subjectPhospholipid-bound choline
dc.subjectEnd stage renal disease
dc.subjectCAPD
dc.subjectPeritoneal dialysis
dc.subjectRat corpus striatum
dc.subjectAcetylcholine-release
dc.subjectParenteral-nutrition
dc.subjectTyrosine-Hydroxylase
dc.subjectPlasma choline
dc.subjectBrain
dc.subjectMetabolism
dc.subjectDeficiency
dc.subjectTransport
dc.subjectCytidine
dc.subjectLiver
dc.subjectMedical laboratory technology
dc.subject.emtreePhospholipid
dc.subject.emtreeCholine
dc.subject.emtreePeritoneal dialysis fluid
dc.subject.emtreePhospholipid
dc.subject.emtreeDialysis fluid
dc.subject.emtreeAdolescent
dc.subject.emtreeAdult
dc.subject.emtreeAged
dc.subject.emtreeArticle
dc.subject.emtreeBlood level
dc.subject.emtreeDialysate
dc.subject.emtreeClinical article
dc.subject.emtreeContinuous ambulatory peritoneal dialysis
dc.subject.emtreeControlled study
dc.subject.emtreeFemale
dc.subject.emtreeHemodialysis patient
dc.subject.emtreeHuman
dc.subject.emtreeKidney disease
dc.subject.emtreeMale
dc.subject.emtreePriority journal
dc.subject.emtreeSchool child
dc.subject.emtreeTreatment outcome
dc.subject.emtreeBlood
dc.subject.emtreeChild
dc.subject.emtreeChronic kidney failure
dc.subject.emtreeColorimetry
dc.subject.emtreeContinuous ambulatory peritoneal dialysis
dc.subject.emtreeMetabolism
dc.subject.emtreeMethodology
dc.subject.emtreeMiddle aged
dc.subject.emtreeVitamin deficiency
dc.subject.meshChild
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshPhospholipids
dc.subject.meshCholine
dc.subject.meshCholine deficiency
dc.subject.meshColorimetry
dc.subject.meshDialysis solutions
dc.subject.meshFemale
dc.subject.meshHuman
dc.subject.meshKidney failure, chronic
dc.subject.meshMale
dc.subject.meshMiddle age
dc.subject.meshPeritoneal dialysis, continuous ambulatory
dc.subject.meshSupport, non-U.S. gov't
dc.subject.scopusCholine; Dimethylglycine; Betaines
dc.subject.wosMedical laboratory technology
dc.titleFree choline and phospholipid-bound choline concentrations in serum and dialysate during peritoneal dialysis in children and adults
dc.typeArticle
dc.wos.quartileQ2
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Nefroloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Farmakoloji ve Klinik Farmakoloji Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

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