Publication:
Expressions of endocan in patients with meningiomas and gliomas

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dc.contributor.authorAtukeren, Pınar
dc.contributor.authorKunbaz, Ahmad
dc.contributor.authorTürk, Okan
dc.contributor.authorKemerdere, Rahsan
dc.contributor.authorUlu, Mustafa Onur
dc.contributor.authorTanrıverdi, Taner
dc.contributor.buuauthorİnanır, Nursel Türkmen
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentAdli Tıp Ana Bilim Dalı
dc.contributor.orcid0000-0002-4047-6455
dc.contributor.scopusid57188706721
dc.date.accessioned2022-12-13T12:52:28Z
dc.date.available2022-12-13T12:52:28Z
dc.date.issued2016-06-30
dc.description.abstractObjective. Endocan has been shown to be a marker for several cancers and may show degree of malignancy. The aim of this study is to assess tissue levels of endocan in common brain tumors, namely, meningiomas, low-grade gliomas (LGGs), and high-grade gliomas (HGGs). Patients and Methods. Endocan was assayed by commercially available enzyme linked immunosorbent assay (ELISA) kits in a total of 50 brain tumors (20 meningiomas, 19 LGGs, and 20 HGGs) and 15 controls. The results were compared to control brain tissues. Results. Each tumor group showed significant higher levels of endocan compared to controls (p < 0.05). In addition, endocan levels showed steady increase from the least (meningiomas) to the most (HGGs) malignant tumors and positive correlation was noted between the degree of malignancy and endocan level (p = 0.0001). Conclusion. Endocan, a vital molecule for angiogenesis, is expressed in common brain tumors and results suggest that endocan could be a marker for malignancy.
dc.description.sponsorshipİstanbul Üniversitesi - 55673
dc.identifier.citationAtukeren, P. vd. (2016). "Expressions of endocan in patients with meningiomas and gliomas". ed. Lance A. L. Disease Markers, 2016.
dc.identifier.issn0278-0240
dc.identifier.issn1875-8630
dc.identifier.pubmed27528791
dc.identifier.scopus2-s2.0-84982153572
dc.identifier.urihttps://doi.org/10.1155/2016/7157039
dc.identifier.urihttps://www.hindawi.com/journals/dm/2016/7157039/
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978841/
dc.identifier.urihttp://hdl.handle.net/11452/29860
dc.identifier.volume2016
dc.identifier.wos000381130500001
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherHindawi
dc.relation.collaborationYurt içi
dc.relation.collaborationSanayi
dc.relation.journalDisease Markers
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBiotechnology & applied microbiology
dc.subjectGenetics & heredity
dc.subjectResearch & experimental medicine
dc.subjectPathology
dc.subjectCell-specific molecule-1
dc.subjectMarker
dc.subjectEsm-1
dc.subjectSurvival
dc.subjectInvasion
dc.subjectCancer
dc.subject.emtreeAnticonvulsive agent
dc.subject.emtreeEndocan
dc.subject.emtreeProtein
dc.subject.emtreeUnclassified drug
dc.subject.emtreeESM1 protein, human
dc.subject.emtreeProteoglycan
dc.subject.emtreeTumor marker
dc.subject.emtreeTumor protein
dc.subject.emtreeAdult
dc.subject.emtreeArticle
dc.subject.emtreeCancer chemotherapy
dc.subject.emtreeCancer radiotherapy
dc.subject.emtreeClinical article
dc.subject.emtreeComparative study
dc.subject.emtreeControlled study
dc.subject.emtreeEnzyme linked immunosorbent assay
dc.subject.emtreeFollow up
dc.subject.emtreeGlioma
dc.subject.emtreeHuman
dc.subject.emtreeHuman tissue
dc.subject.emtreeMeningioma
dc.subject.emtreeNuclear magnetic resonance imaging
dc.subject.emtreeOverall survival
dc.subject.emtreeProtein determination
dc.subject.emtreeProtein expression
dc.subject.emtreeSeizure
dc.subject.emtreeSurvival time
dc.subject.emtreeBrain tumor
dc.subject.emtreeCancer staging
dc.subject.emtreeCase control study
dc.subject.emtreeFemale
dc.subject.emtreeGlioma
dc.subject.emtreeMale
dc.subject.emtreeMeningioma
dc.subject.emtreeMetabolism
dc.subject.emtreePathology
dc.subject.emtreePrognosis
dc.subject.meshAdult
dc.subject.meshBiomarkers, tumor
dc.subject.meshCase-control studies
dc.subject.meshBrain neoplasms
dc.subject.meshEnzyme-linked immunosorbent assay
dc.subject.meshFemale
dc.subject.meshFollow-up studies
dc.subject.meshGlioma
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMeningeal neoplasms
dc.subject.meshMeningioma
dc.subject.meshNeoplasm proteins
dc.subject.meshNeoplasm staging
dc.subject.meshPrognosis
dc.subject.meshProteoglycans
dc.subject.scopusDermatan Sulfate Proteoglycan; Human ESM1 Protein; Proteoglycan
dc.subject.wosBiotechnology & applied microbiology
dc.subject.wosGenetics & heredity
dc.subject.wosMedicine, research & experimental
dc.subject.wosPathology
dc.titleExpressions of endocan in patients with meningiomas and gliomas
dc.typeArticle
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Adli Tıp Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

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