Publication:
Treatment of infective endocarditis with recombinant tissue plasminogen activator

dc.contributor.buuauthorGüneş, Adalet Meral
dc.contributor.buuauthorMERAL GÜNEŞ, ADALET
dc.contributor.buuauthorBaytan, Birol
dc.contributor.buuauthorSemizel, Evren
dc.contributor.buuauthorBostan, Özlem Mehtap
dc.contributor.buuauthorBOSTAN, ÖZLEM MEHTAP
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentÇocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.contributor.orcid0000-0001-7707-2174
dc.contributor.orcid0000-0002-9375-2855
dc.contributor.researcheridAAG-8558-2021
dc.date.accessioned2024-10-18T11:19:00Z
dc.date.available2024-10-18T11:19:00Z
dc.date.issued2008-01-01
dc.description.abstractInfective endocarditis (IE) caused by microbial infection is virtually always fatal if untreated. High-dose and long-term antibiotic treatment is required to eradicate microorganisms. If increased risk of embolic events, persistent infection, and progressive cardiac failure are present, surgery is indicated. However, surgery can carry an increased risk of mortality and morbidity in critically ill children of whom other treatment options Such as administering, a thromholytic agent; recombinant tissue plasminogen activator (r-tPA) could be an alternative choice. Here, we report a 14-year-old male with Down syndrome and acute myeloblastic leukemia, diagnosed with IE characterized by two large vegetations on aortic and mitral valves, who was successfully treated with r-tPA.
dc.identifier.doi10.1002/pbc.20890
dc.identifier.endpage134
dc.identifier.issn1545-5009
dc.identifier.issue1
dc.identifier.startpage132
dc.identifier.urihttps://doi.org/10.1002/pbc.20890
dc.identifier.urihttps://hdl.handle.net/11452/46722
dc.identifier.volume50
dc.identifier.wos000251410400026
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherWiley-liss
dc.relation.journalPediatric Blood & Cancer
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectThrombolytic therapy
dc.subjectChildren
dc.subjectManagement
dc.subjectDiagnosis
dc.subjectInfants
dc.subjectChildren
dc.subjectInfective endocarditis
dc.subjectR-tpa
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectOncology
dc.subjectPediatrics
dc.subjectHematology
dc.titleTreatment of infective endocarditis with recombinant tissue plasminogen activator
dc.typeArticle
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Hematoloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
relation.isAuthorOfPublication500825a8-5e0f-481f-a84f-d7fb8759c049
relation.isAuthorOfPublication11a8d258-960b-43e2-afd8-14f539da4b93
relation.isAuthorOfPublication.latestForDiscovery500825a8-5e0f-481f-a84f-d7fb8759c049

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