Publication: GO-BEYOND: a real-world study of persistence of golimumab in patients with axial spondyloarthritis and rheumatoid arthritis in Turkey
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Authors
Akar, Servet
Kalyoncu, Umut
Dalkılıç, Ediz
Emmüngil, Hakan
Aziz, Ayten
Esen, Yasemin
Koç, Tuba
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Future Medicine
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Abstract
Aim: To evaluate the retention rate of golimumab (GLM) in patients with rheumatoid arthritis (RA) and axial spondyloarthritis (ax-SpA). Materials & methods: Patients had received/were receiving GLM as their first or second biological drug for at least 3 months. We recorded demographic and clinical data, data on drug continuation and disease activity. Patients were classified as biologic-naive and biologic-experienced. Results: The study included 60 RA and 269 ax-SpA patients. At month 24, the retention rates were 67.2 and 57.1% (biologic-naive and biologic-experienced RA) and 74.8 and 80.4% (anti-TNF-naive and -experienced ax-SpA). No significant differences in retention were observed between the biologic-naive and -experienced groups for either disease. Conclusion: The results of this study confirm the effectiveness of GLM in the treatment of RA and axSpA with good retention rates at 2 years in a real-world setting in Turkey.
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Keywords
Axial spondyloarthritis, Biologic, Efficacy, Golimumab, Retention, Rheumatoid arthritis, TNF-α, Inhibitor, Immunology